催产素联合冰袋、米索前列醇、卡孕栓预防产后出血的研究

[目的]观察催产素联合应用冰袋、米索前列醇、卡孕栓预防产后出血的临床效果 [方法] 选择2010年4月至2010年9月本院住院的产妇312例,其中阴道分娩177例,剖宫产135例.阴道分娩组分A,B,C,D四组.A组：单用催产素;B组：催产素联合冰袋;C组：催产素联合米索前列醇;D组：催产素联合卡孕栓.剖宫产组分为E,F,G三组.E组：单用催产素;F组：催产素联合米索前列醇;G组：催产素联合卡孕栓.观察比较各组第三产程时间、术中出血量,产后2 h出血量、产后24 h出血量、产后出血发生率、治疗前后的血压及心率变化.[结果]B组、C组、D组第三产程与A组相比明显缩短,产后2 h及24 h内出血量,产后出血发生率明显减少,且差异有统计学意义（P＜0.05）.F组、G组与E组相比,第三产程明显缩短,产后2 h及24 h内出血量,产后出血发生率明显减少,且差异有统计学意义（P＜0.05）.各组治疗前后血压、脉搏无明显波动（P＞0.05）.[结论]催产素联合应用冰袋、米索前列醇、卡孕栓能预防产后出血,其使用安全,值得临床推广

Study on Oxytocin Combined with Ice Pack, Misoprostol and Carboprost Methylate Suppositories for the Prevention of Postpartum Hemorrhage

[Objective] To observe the clinical efficacy of oxytocin combined with ice pack, misoprostol orcarboprost methylate suppositories for the prevention of postpartum hemorrhage. [Methods] Totally 312 parturients in our hospital from April 2010 to September 2010 were selected. Among all cases, 177 cases underwent vaginal delivery and I35 cases underwent cesarean section. The vaginal delivery group was divided into 4 groups. Group A was treated with simple oxytocin. Group B was treated with oxytocin combined with ice pack. Group C was treated with oxytocin combined with misoprostol. Group D was treated with oxytocin combined with carboprost methylate suppositories. The cesarean section group was divided into 3 groups. Group E was treated with simple oxytocin. Group F was treated with oxytocin combined with misoprostol. Group G was treated with oxytocin combined with carboprost methyl carboprost suppository. The time of third stage of labor, intraoperative blood loss, the volume of blood loss at 2h and 24h after delivery, the incidence of postpartum hemorrhage, blood pressure and heart rate variation before and after treatment were observed, [Resuits]In group B, C and D, the third stage of labor was obviously shortened, and the volume of blood loss within 24h and the incidence of postpartum hemorrhage obviously decreased in comparison with group A, and the differences had statistical significance（ P %0.05）. Compared with group E, the third stage of labor was shortened, and the volume of blood toss within 2h and 24h after delivery and the incidence of postpartum hem- orrhage obviously decreased in group F and G, and the differences had statistical significance（ P 〈0.05）. The fluctuation of blood pressure and pulse in all groups before and after treatment was not significant（ P 〉0.05）. [Conclusion] Oxytocin combined with ice pack, misoprostol or carboprost methylate suppositories can prevent the postpartum hemorrhage. They are safe and worthy of clinical application.