| 黄蒲通窍胶囊治疗血管性痴呆的临床观察 |
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| 引用本文： | 陈永华,江停战,张波,黄为,刘妮,曹仕健,王时光,李亚军.黄蒲通窍胶囊治疗血管性痴呆的临床观察[J].中西医结合心脑血管病杂志,2010,8(1):41-43. |
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| 作者姓名： | 陈永华 江停战 张波 黄为 刘妮 曹仕健 王时光 李亚军 |
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| 作者单位： | 安徽省中医院,230031 |
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| 摘 要： | 目的观察黄蒲通窍胶囊治疗血管性痴呆(VaD)患者的临床疗效及安全性。方法将符合纳入病例标准的90例VaD患者随机分成3组,即西药多奈哌齐治疗组(A组),中医辨证后运用黄蒲通窍胶囊组(B组)和中医辨证后使用黄蒲通窍胶囊合用多奈哌齐组(C组)。疗程为60d。观察3组治疗后中医证候积分;神经心理学量表检查包括:简明精神状态检查量表(MMSE)、日常生活能力量表(ADL)、阿尔茨海默病评定量表-认知分量表(ADAS-Cog)。测定血液流变学及血清同型半胱氨酸(Hcy)。结果黄蒲通窍胶囊可以显著改善中医证候积分、ADL、MMSE、ADAS-cog积分,降低血Hcy且无明显不良反应。结论黄蒲通窍胶囊可以改善VaD患者的临床症状,是治疗血管性痴呆的安全有效药物。
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| 关 键 词： | 血管性痴呆 黄蒲通窍胶囊 多奈哌齐 血清同型半胱氨酸 |
Clinical Observation on Huangputongqiao Capsule in Treatment of Vascular Dementia |
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| Chen Yonghua,Jiang Tingzhan,Zhang Bo,et al Cadre.Clinical Observation on Huangputongqiao Capsule in Treatment of Vascular Dementia[J].Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease,2010,8(1):41-43. |
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| Authors: | Chen Yonghua Jiang Tingzhan Zhang Bo Cadre |
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| Institution: | Chen Yonghua,Jiang Tingzhan,Zhang Bo,et al Cadre Department of Neurology,Anhui Hospital of Traditional Chinese Medicine(Hefei 230031) |
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| Abstract: | Objective To observe the effect of Huangputongqiao capsule in treatment of patients with vascular dementia(VaD).Methods Ninety patients with vascular dementia were randomly divided into three groups:Donepenil group (A group) treated with donepenil,Huangputongqiao capsule group (B group) treated with Huangputongqiao capsule,donepenil with huangputongqiao capsule group (C group) treated with donepenil and huangputongqiao capsule. The scores of TCM symptom,activity of daily living(ADL)scale,mini-mental state e... |
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| Keywords: | vascular dementia Huangputongqiao capsule donepenil homocysteine |
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