肺癌组织内肺动脉灌注血管立体构筑

目的：为探讨肺癌介入治疗宜采用的动脉，研究肺癌组织内肺动脉的立体构筑。方法：５ 例手术切除肺癌标本应用１０ ％ ＡＢＳ丙酮液从肺动脉高压灌注进行肿瘤血管铸型，并在立体显微镜下观察肺癌组织肺动脉立体构筑。７８ 例支气管动脉造影资料进行回顾性分析。光学显微镜下观察肺癌组织内毛细血管床。结果：按动脉分布，肺癌组织可分为三个不同区带：支气管动脉主要供应肺癌的中心区；肺癌外带肺动脉相对密集，呈向心直行并互相吻合；癌周组织带有粗大纡曲走行的动脉，向肺癌组织内或包膜内延伸。结论：证实肺动脉参与肺癌供血。认为晚期肺癌单纯支气管动脉灌注化疗（ＢＡＩ）中，宜辅以肺动脉灌注化疗（ＰＡＩ）。

Study of Pulmonary Artery Supply in Lung Cancer Casts

Purpose: Seeking better arterial route in intervening chemotherapy for lung cancer the 3-dimentional architecture of pulmonary arteries were studied. Methods: 10?S in acetone was injected into 5 fresh lung cancer specimens by way of the pulmonary artery after which the architecture of the pulmonary arterial distribution in cancer tissues was observed under stereomicroscope. Bronchoarterial distributive pattern in 78 cases of lung cancer sections were analysed by reviewing the capillary bed in tumor tissue under optic microscope. Results: Bronchial arterial tributaries were seen mainly in the central part of the tumor. Pulmonary artery ramifications were seen crowded in the outer zone of the specimen and ran centripetally with anastomoses to each other. In the pericancerous outer zone, coarse arteries ran zigzag and extended into the tumor. Conclusion:It is demonstrated that pulmonary artery provides blood supply to lung cancer.It is logical that pulmonary artery infusion (PAI) be used as a supplementary treatment of bronchial artery infusion (BAI) chemotherapy in late stage lung cancer.