| 高血压合并阻塞性睡眠呼吸暂停综合征与血清5-羟色胺水平的关系 |
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| 引用本文： | 张艳玲,雷飞,杨中华. 高血压合并阻塞性睡眠呼吸暂停综合征与血清5-羟色胺水平的关系[J]. 华西医学, 2008, 23(1): 43-44 |
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| 作者姓名： | 张艳玲 雷飞 杨中华 |
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| 作者单位： | 1. 四川大学华西医院,老年科,四川成都,610041
2. 四川大学华西医院,呼吸内科,四川成都,610041 |
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| 摘 要： | 目的:探讨高血压合并阻塞性睡眠呼吸暂停综合征(OSAS)患者血浆5-羟色胺(5-HT)水平的变化。方法:应用放射免疫法测定45例高血压合并阻塞性睡眠呼吸暂停综合征患者血清5-HT浓度。结果:高血压合并阻塞性睡眠呼吸暂停综合症患者与单纯高血压不合并OSAS的患者相比,血压控制较差,而血浆5-HT水平明显增高(P<0.05),轻、中、重度阻塞性睡眠呼吸暂停综合征患者血浆5-HT水平之间相比较有差异(P<0.05)。结论:5-HT水平可能与血压控制和阻塞性睡眠呼吸暂停综合征的发病有关。
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| 关 键 词： | 5-羟色胺 高血压 阻塞性睡眠呼吸暂停综合征 |
| 文章编号： | 1002-0179(2008)01-0043-02 |
| 修稿时间： | 2007-07-22 |
The Correlation of Plasma 5-hytroxytryptamine and Hypertension Associated with Obstructive Sleep Apnea Syndrome |
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| ZHANG Yan-ling,LEI Fei,YANG Zhong-hua. The Correlation of Plasma 5-hytroxytryptamine and Hypertension Associated with Obstructive Sleep Apnea Syndrome[J]. West China Medical Journal, 2008, 23(1): 43-44 |
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| Authors: | ZHANG Yan-ling LEI Fei YANG Zhong-hua |
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| Abstract: | Objective:To study the changes of plasma 5-hytroxytryptamine(5-HT)in patients with hypertensions associated with obstructive sleep apnea syndrome(OSAS).Methods:5-HT concentrations in the plasma from 45 cases of hypertension and OSAS were determined by radioimmunoassay.Results:Blood pressures were higher,and 5-HT concentrations increased significantly in the mild,moderate and severe OSAS and hypertension patients than that of patients with hypertension alone(P<0.05).There were significant differences between mile,moderate,and severe OSAS groups(P<0.05).Conclusion:5-HT may involve in the course of OSAS and the control of hypertension. |
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| Keywords: | 5-hytroxytryptamine hypertension obstructive sleep apnea syndrome(OSAS) |
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