| 局麻止痛膜的制备及质量控制 |
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| 引用本文： | 杨宝峰,韩永龙,宫学惠,董慧萍,李丽辉.局麻止痛膜的制备及质量控制[J].中国药房,2005,16(22):1712-1713. |
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| 作者姓名： | 杨宝峰 韩永龙 宫学惠 董慧萍 李丽辉 |
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| 作者单位： | 黑龙江大庆油田总医院,大庆市,163001 |
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| 摘 要： | 目的:制备局麻止痛膜并建立其质量控制方法。方法:以聚乙烯醇-124为基质制备局麻止痛膜,并采用高效液相色谱法测定其中主药盐酸达克罗宁的含量。结果:盐酸达克罗宁检测浓度在40.8~408μg/ml范围内与峰面积线性关系良好(r=0.9 998),平均回收率为101.3%(RSD=1.3%,n=6)。结论:局麻止痛膜的制备工艺简单,质量稳定,控制方法可行。
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| 关 键 词： | 局麻止痛膜 盐酸达克罗宁 制备 质量控制 |
| 文章编号： | 1001-0408（2005）22-1712-02 |
| 收稿时间： | 2005-04-05 |
| 修稿时间： | 2005-06-17 |
Preparation and Quality Control of Jumazhitong Film |
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| YANG Baofeng,HAN Yonglong,GONG Xuehui,DONG Huiping,LI Lihui.Preparation and Quality Control of Jumazhitong Film[J].China Pharmacy,2005,16(22):1712-1713. |
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| Authors: | YANG Baofeng HAN Yonglong GONG Xuehui DONG Huiping LI Lihui |
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| Institution: | The Daqing Oilfield Hospital in Heilongjiang Province, Daqing 163001, China |
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| Abstract: | OBJECTIVE:To prepare jumazhitong film and establish its quality control method.METHODS:The jumazhitong film former was made with PVOH-124 as the base,the content of the principal agent-dyclonine hydrochloride was determined by HPLC.RESULTS:Good linear relation was achieved when the detection concentration range of dyclonine hydrochloride was 40.8～408μg/ml(r=0.9 998),the average recovery was 101.3%(RSD=1.3%,n=6).CONCLUSION:The preparing technique of jumazhitong film former is simple,its quality is stable and the control method is feasible. |
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| Keywords: | Jumazhitong film Dyclonine hydrochloride Preparation Quality control |
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