Intense accumulation of 18F-FDG, not enhancement on MRI, helps to guide the surgical biopsy accurately in soft tissue tumors |
| |
| Authors: | Jong Hoon Park Eun Kyung Park Chang Ho Kang Chul Hwan Kim Jae Gol Choe Won Noh |
| |
| Affiliation: | (1) Department of Orthopedic Surgery, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea;(2) Department of Nuclear Medicine, Korea University Anam Hospital, Korea University College of Medicine, 126-1, 5 ga, Anam-dong, Seongbuk-gu, Seoul, 136-705, Korea;(3) Department of Radiology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea;(4) Department of Pathology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea; |
| |
| Abstract: | Soft tissue sarcomas are a highly heterogeneous group of malignancies that arise from mesenchymal tissues. Grading of soft tissue sarcomas is an important prerequisite for the choice of therapy and estimation of prognosis. However, incisional biopsy of huge soft tissue sarcoma lesions frequently fails to provide an accurate diagnosis when there is a benign component, cystic changes and/or necrosis. MRI is helpful in evaluating the extent of the sarcoma lesion, vascularization, invasiveness and integrity of surrounding tissue, but definitive differentiation of benignity and malignancy is not possible with it. In this study, positron emission tomography using [18F]-2-fluoro-2-deoxy-d-glucose successfully guided surgeons to identify the most hypermetabolic and, therefore, the most suitable biopsy sites of huge soft tissue sarcoma. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
