急性缺血性脑卒中并发院内获得性肺炎患者预后危险因素分析

目的探讨影响急性缺血性脑卒中并发院内获得性肺炎患者预后的危险因素。方法回顾分析46例急性缺血性脑卒中并发院内获得性肺炎患者(研究组)和54例排除院内获得性肺炎急性缺血性脑卒中患者(对照组)的临床资料,分析与Barthel指数有关的因素。结果研究组预后效果明显差于对照组,Barthel指数显著低于对照组(P<0.05)。单因素分析年龄、收缩压、舒张压、FPG、HbA1c、入院NIHSS、入院GCS、30 s反复唾液吞咽次数、PA、MRSA、MDRAB、CA与Barthel指数的关系均有统计学意义(P<0.05)。多因素分析年龄、HbA1c、入院NIHSS、30 s反复唾液吞咽次数、PA、MRSA、MDRAB、CA是影响Barthel指数的独立危险因素(P<0.05)。结论急性缺血性脑卒中并发院内获得性肺炎患者预后与年龄、糖代谢、神经功能损伤、病原菌感染和耐药密切相关。

Study of the risk factors of prognostic for acute stroke patients with hospital-acquired pneumonia

Objective To investigate the risk factors of prognostic for acute stroke patients with hospital-acquired pneumonia. Methods A retrospective analysis of the clinical date of 46 acute stroke patients with hospital acquired pneumonia patients （study group） and 54 acute stroke patients exclude hospital-acquired pneumonia （control group） were selected, and the related factors of the Barthel Index were analyzed. Results The study group prognosis was significantly worse than the control group. Barthel Index was significantly lower than the control group （P 〈0.05）. Univariate analysis, age, systolic blood pressure, diastolic blood pressure, FPG and HbAlc, hospitalized NIHSS, hospitalized GCS, the relationship between the number of 30 s repeated saliva swallowing, PA, MRSA and MDRAB, the CA with the Barthel index were statistically significant （P 〈0.05）. Multivariate analysis, age, HbAlc, admission, the NIHSS, 30 s repeated saliva swallowing times, the PA MRSA, MDRAB, CA were the risk factors for the Barthel Index （P 〈0.05）. Conclusion The prognosis of acute stroke patients with hospital acquired pneumonia might be closely related with age, glucose metabolism, neurological injury, pathogen infection and drug resistance.