| 激肽释放酶14在卵巢癌组织中的表达及临床意义 |
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| 引用本文： | 颜秋梅,李巧云,闻立红. 激肽释放酶14在卵巢癌组织中的表达及临床意义[J]. 中国实用医药, 2013, 0(11): 28-29 |
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| 作者姓名： | 颜秋梅 李巧云 闻立红 |
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| 作者单位： | 郑州大学第五附属医院妇产科,450052 |
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| 摘 要： | 目的探讨激肽释放酶14（kallikrein14）在卵巢癌组织的表达及临床意义。方法应用SP和ELISA法检测不同卵巢患者KLK14蛋白的表达和KLK14血清学的浓度。结果卵巢癌组KLK14蛋白表达阳性率／血清学浓度明显高于卵巢良性上皮肿瘤组和正常卵巢组。KLK14蛋白表达与卵巢癌患者的临床分期，组织学分级有关。结论KLK14过表达与卵巢癌的发生、侵袭相关，提示其可能成为卵巢癌的标志物。
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| 关 键 词： | 肿瘤标志物 卵巢上皮性恶性肿瘤 KLK14 SP ELISA |
Kallikrein 14 in ovarian cancer tissues and its clinical significance |
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| Affiliation: | YAN Qiu-mei, LI Qiao-yun, WEN Li- hong. (Obstetrics and Gynecology, The Fifth Affiliated Hospital of Zhengzhou University, Henan 450052, China) |
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| Abstract: | Objective To investigate the effect of kallikrein 14 （kallikreinl4） expression in ovarian carcinoma and its clinical significance. Methods The concentration of different ovarian patients with KLK14 protein was detected by SP and ELISA expression and KLK14 serology. Results The expression of ovarian cancer group the positive rate of KLK14 protein in serum concentrations were significantly higher than benign epithelial ovarian tumor and normal ovarian group. The expression of KLK14 protein in ovarian cancer patients with clinical stages, histological classification, Conclusion Overexpression of KLK14 and ovarian cancer,invasiveness, suggesting that it may become a marker in ovarian cancer. |
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| Keywords: | Tumor marker Epithelial ovarian cancer KLK14 SP ELISA |
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