|
|||||
|
|
| BDNF对大鼠急性高眼压后视网膜电图的影响 | |
| 引用本文： | 刘求理 潘爱华. BDNF对大鼠急性高眼压后视网膜电图的影响[J]. 湖南医科大学学报, 1998, 23(2): 123-125 |
| 作者姓名： | 刘求理 潘爱华 |
| 摘 要： | 在大鼠玻璃体内注射脑源性神经营养因子（ＢＤＮＦ）或正常羊血清（对照），观察对急性高眼压后视网膜电图的影响。急性高眼压后３天，实验组视网膜电图ｂ波恢复程度明显高于对照组（Ｐ〈０．０１）。提示ＢＤＮＦ能促进急性高眼压后视网膜电生理功能的恢复。 |
| 关 键 词： | 高眼压损伤 神经营养因子 视网膜电图 BDNF |
The effect of brain-derived neurotrophic factor on the rat electroretinography after pressure-induced ischemic injury] |
|
| Q Liu,A Pan,X Wen,X Luo. The effect of brain-derived neurotrophic factor on the rat electroretinography after pressure-induced ischemic injury][J]. Bulletin of Hunan Medical University, 1998, 23(2): 123-125 | |
| Authors: | Q Liu A Pan X Wen X Luo |
| Affiliation: | Department of Neurobiology, Hunan Medical University, Changha. |
| Abstract: | Brain-derived neurotrophic factor (BDNF) or normal goat serum (NGS) was injected intravitreously in each 11 wistar albino rats two days before the induction of ischemia. Retinal ischemia was induced in 22 rats by increasing intraocular pressure to the threshold level which extinguished the electroretinography (ERG) b-wave individually, and maintaining for 90 minutes. The ERG b-wave of the BDNF-treated rats recovered to 80.5 +/- 24.4% of their normal amplitude three days after ischemia, while that of the NGS-treated rats recovered only to 11.1 +/- 5.3%. Statistic analysis showed that the recovery level of ERG b-wave after ischemia in the BDNF and NGS treated rats was significantly different (P < 0.01). The results suggest that BDNF could promote the recovery of the retinal electrophysiologic function from ischemia induced by high intraocular pressure. |
| Keywords: | |
| 本文献已被 维普 等数据库收录！ | |