巨大儿相关因素的前瞻性初步研究

观察１１０例孕妇孕期增重，５０ｇ葡萄糖筛选试验血糖（５０ｇＧＣＴ），母血及脐血胰岛素（ＩＮＳ），生长激素（ＧＨ）及脐血糖与新生儿体重的关系。结果发现，孕期增重≥１５ｋｇ者巨大儿发生率明显增高；巨大儿组５０ｇＧＣＴ血糖明显高于非巨大儿组，提示孕期增重、５０ｇＧＣＴ可作为预测巨大儿相关参数。

Prospective study on the correlation factors of fetal macrosomia]

The increase of body weight in pregnancy women, 50 g oral glucose challenge test (50 g GCT), pregnant women and umbilicus vein blood insulin (INS), growth hormone (GH), glucose and neonate weight were measured in 110 pregnant women and their neonates were measured to explore the correlation factors of fetal macrosomia. The incidence of macrosomia was higher in pregnant women whose increased weight > or = 15 kg than those < 15 kg. 50 g GCT plasma glucose showed positive correlation with neonatal weight. Which was higher in the group of the fetal macrosomia than of the normal neonates. The results suggest that both the increasing weight of the pregnant women and the 50 g GCT are related parameters to predict fetal macrosomia. To prevent fetal macrosomia the diet should be limited in those who have had a high increasing body weight in pregnancy and appropriate intervention is required to those whose 50 g GCT are positive.