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外周血嗜酸性粒细胞计数与中老年人冠状动脉钙化的关系
引用本文:程序,杨忖卿,石凤祥,孙黎,庞博,谷春,侯雪筠,费佳欣,刘贵建. 外周血嗜酸性粒细胞计数与中老年人冠状动脉钙化的关系[J]. 国际检验医学杂志, 2022, 0(3): 309-312
作者姓名:程序  杨忖卿  石凤祥  孙黎  庞博  谷春  侯雪筠  费佳欣  刘贵建
作者单位:中国中医科学院广安门医院检验科;中国中医科学院广安门医院放射科
基金项目:中华国际科学交流基金会检验检测科技专项基金(Z2019LBJ003)。
摘    要:
目的 探讨外周血嗜酸性粒细胞计数与中老年人冠状动脉钙化的关系.方法 选取2021年2-5月就诊于本院、年龄>40岁并行CT冠状动脉造影的患者118例为研究对象,评估冠状动脉钙化评分(CACS)与外周血嗜酸粒细胞计数及主要心血管危险因素(包括年龄、吸烟状况、高血压、血脂异常、糖尿病)的关系.结果 女性外周血嗜酸性粒细胞计...

关 键 词:嗜酸性粒细胞  冠状动脉钙化  动脉粥样硬化  中老年人

Relationship between peripheral blood eosinophil count and coronary artery calcification in middle-aged and elderly people
CHENG Xu,YANG Cunqing,SHI Fengxiang,SUN Li,PANG Bo,GU Chun,HOU Xueyun,FEI Jiaxin,LIU Guijian. Relationship between peripheral blood eosinophil count and coronary artery calcification in middle-aged and elderly people[J]. International Journal of Laboratory Medicine, 2022, 0(3): 309-312
Authors:CHENG Xu  YANG Cunqing  SHI Fengxiang  SUN Li  PANG Bo  GU Chun  HOU Xueyun  FEI Jiaxin  LIU Guijian
Affiliation:(Department of Clinical Laboratory,Guang′anmen Hospital of China Academy of Chinese Medical Sciences,Beijing 100053,China;Department of Radiology,Guang′anmen Hospital of China Academy of Chinese Medical Sciences,Beijing 100053,China)
Abstract:
Objective To investigate the relationship between peripheral blood eosinophil count and coronary artery calcification in middle-aged and elderly people.Methods A total of 118 patients who were admitted to our hospital from February to May 2021,more than 40 years old and underwent CT coronary angiography were selected as the research subjects.The relationship between coronary artery calcium score(CACS)and peripheral blood eosinophil count and major cardiovascular risk factors(including age,smoking status,hypertension,dyslipidemia,and diabetes mellitus)were evaluated.Results The peripheral blood eosinophil count in women was significantly lower than that in men(P=0.001),and the peripheral blood eosinophil count in diabetic patients was significantly higher than that in non-diabetic patients(P=0.038).The log(CACS+1)of patients with hypertension was significantly higher than that of patients without hypertension(P=0.036),and the log(CACS+1)of patients with dyslipidemia was significantly higher than that of patients with normal blood lipids(P=0.019).The log(CACS+1)of the high eosinophil group was higher than that of the low eosinophil group(P=0.0147).Conclusion There is a certain relationship between peripheral blood eosinophil count and coronary artery calcification in middle-aged and elderly people.
Keywords:eosinophils  coronary calcification  atherosclerosis  middle-aged and elderly people
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