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慢性丙型肝炎患者血清IGF-Ⅰ水平与血清HA、PⅢP关系的探讨
引用本文:李勇,孙业富,夏爱萍.慢性丙型肝炎患者血清IGF-Ⅰ水平与血清HA、PⅢP关系的探讨[J].放射免疫学杂志,2008,21(2):121-122.
作者姓名:李勇  孙业富  夏爱萍
作者单位:1. 高邮市中医院检验科,225600
2. 扬州市中心血站商邮分站
3. 高邮市人民医院
摘    要:目的:探讨了慢性丙型肝炎患者血清IGF-Ⅰ水平及其与血清HA、PⅢP的关系。方法:采用放射免疫分析对39例慢性丙型肝炎患者进行了血清IGF-Ⅰ和HA、PⅢP含量测定,并与35名正常健康人作比较。结果:慢性丙型肝炎患者血清IGF-Ⅰ水平与HA、PⅢP水平呈明显正相关(r=0.8018、0.7126,P〈0.01)。结论:检测慢性丙型肝炎患者血清IGF-Ⅰ和HA、PⅢP水平的变化对疾病的诊断、治疗是一个十分有用的临床检测指标。

关 键 词:慢性丙型肝炎  胰岛素样生长因子-Ⅰ  透明质酸  胶原蛋白-Ⅲ
修稿时间:2008年1月12日

Study on the Correlationship Between Serum IGF-Ⅰ and HA,P Ⅲ P Levels in Patients with Chronic Hepatitis C
Li Yoag,Sun Yefu,Xia Aiping.Study on the Correlationship Between Serum IGF-Ⅰ and HA,P Ⅲ P Levels in Patients with Chronic Hepatitis C[J].Journal of Radioimmanology,2008,21(2):121-122.
Authors:Li Yoag  Sun Yefu  Xia Aiping
Abstract:Objective To study the inter - relationship between serum IGF - Ⅰ and HA, P Ⅲ P levels in patients with chronic hepatitis C. Methods Serum IGF - Ⅰ , HA and P III P levels were determined with RIA in 39 patients with chronic hepatitis C and 35 controls. Results Serum IGF - Ⅰ, HA and PⅢP levels in the patients were significantly higher than those in controls (P〈0.01). The serum IGF - Ⅰ levels and HA, PⅢP levels were mutually positively correlated (r =0. 8018,0. 7126, P 〈0.01). Conclusion Serum IGF- Ⅰ , HA and PⅢP were useful diagnostic markers in patients with chronic hepatitis C.
Keywords:elronie hepatitis  insulin-like growth factor-Ⅰ(IGF-Ⅰ)  hyaluronie acid (HA)  proeollagen type Ⅲ (PⅢP)
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