| 骨髓增生异常综合征淋巴细胞及单核细胞生成白细胞介素6检测 |
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| 引用本文： | 袁潮,伍柏松.骨髓增生异常综合征淋巴细胞及单核细胞生成白细胞介素6检测[J].中华血液学杂志,1995,16(2):84-86. |
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| 作者姓名： | 袁潮 伍柏松 |
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| 作者单位： | 北京军区总医院，南方医院，西安第四军医大学 |
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| 摘 要： | ２６例骨髓增生异常综合征（ＭＤＳ）外周血淋巴、单核细胞在不同状态时生成白细胞介素６（ＩＬ－６）水平用生物法检测，发现：患者淋巴细胞在无丝裂原刺激时生成ＩＬ－６与正常人无差异（Ｐ〉０．０５），刺激后ＲＡＥＢ及ＲＡＥＢ－ｔ者低于正常（Ｐ〈０．０５，Ｐ〈０．０１）；患者单核细胞在无刺激状态下生成水平高于正常人（Ｐ〈０．０５或Ｐ〈０．０１），刺激后ＲＡＥＢ及ＲＡＥＢ－ｔ者则低于正常人（Ｐ〈０．０１）。认为
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| 关 键 词： | 骨髓增生异常 综合征 白细胞介素6 淋巴细胞 |
DETECTON OF IL-6 PRODUCTION FROMLYMPHOCYTES AND MONOCYTES iN PATIENTS WITHMYELODYSPLASTIC SYNDROMES |
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| Yuan Chao, Wu Bosong,Huang Chuanshu et at.DETECTON OF IL-6 PRODUCTION FROMLYMPHOCYTES AND MONOCYTES iN PATIENTS WITHMYELODYSPLASTIC SYNDROMES[J].Chinese Journal of Hematology,1995,16(2):84-86. |
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| Authors: | Yuan Chao Wu Bosong Huang Chuanshu et at |
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| Abstract: | ith or without mitogen stimulation, the produc-tion of IL-6 by peripheral lymphocyte and monocyte wasbioassayed in 26 cases of myelodysplastic syndromes(MDS) (RA 11 ,RAEB 8 ,RAEBt 7 cases). The resultsshowed that IL-6 released by the patients' unstimulatedlymphocytes and monocytes was at the same level as andhigher than that of the normal controls, respectively.However, the IL-6 production by the stimulated lyrnpocytes and monocytes of the patients with RAEB orRAEBt subtypes was lower than that of the normal con-trols. |
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| Keywords: | Myelodysplastic syndromes Interleukin-6 Lymphocyte Mono-cyte |
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