正畸微种植体表面阳极氧化处理对周围骨组织的影响

目的通过组织形态学及组织形态测量学评价正畸微螺旋种植体表面阳极氧化处理对周围骨组织愈合情况的影响。方法24枚钛合金正畸用微螺旋种植体种植于两只新西兰大白兔的后腿，在闭合环境下生长6周。12枚微种植体经过表面阳极氧化处理作为研究组；另外12枚表面没有经过任何处理作为对照组。兔处死后，部分微种植体及周围骨组织进行组织学苏木精-伊红染色（hematoxylin-eosin staining，HE）处理，每组有4枚微种植体及周围骨组织块采用维拉努埃瓦（Villanueva）染色。光学显微镜评价种植体的组织学变化并计算种植体的骨结合率。结果两组种植体均与周围骨组织有一定的结合，其间无结缔组织可见。螺旋区骨纤维走向紊乱，表面阳极氧化组微种植体周围有较多的骨组织可见。阳极氧化组微种植体的骨结合率略高于对照组。结论阳极氧化处理可能促进钛合金微种植体与周围骨组织的结合。

Effect of anodized oxidation on the surrounding tissue of orthodontic microscrew implants

Objective To evaluate the effect of anodized oxidation of Ti-alloy microscrew implants on the osseointegration. Methods Twenty-four Ti-alloy microscrew implants were inserted in the femurs in two rabbits for six weeks. Half of the implants were pretreated in anodized solution as experimental group and others not treated as controls. Undecalcified and decalcified sections of the implants and surrounding tissue were examined with light microscope and the osseointegration rate was calculated. Results Osseointegration was seen in all samples in both groups and no fibrous tissue was seen between bone and implant. The osseointegration rate was slightly higher in the experimental group than in the controls. Conclusions Anodized oxidation could improve the osseointegration rate of Ti-aUoy microscrew implants.