| 外泌体在乳腺癌发病中的作用机制 |
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| 引用本文： | 晏芾,于韶荣,曹海霞,冯继锋. 外泌体在乳腺癌发病中的作用机制[J]. 国际肿瘤学杂志, 2016, 0(6): 462-464. DOI: 10.3760/cma.j.issn.1673-422X.2016.06.017 |
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| 作者姓名： | 晏芾 于韶荣 曹海霞 冯继锋 |
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| 作者单位： | 210009,南京医科大学附属江苏省肿瘤医院肿瘤内科 |
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| 基金项目： | 江苏省自然科学基金(BK20141016、BK20141017) Natural Science Foundation of Jiangsu Province of China (BK20141016 |
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| 摘 要： | 研究表明外泌体可通过介导细胞间通讯参与乳腺癌的发生发展过程,促进肿瘤转移和耐药,影响肿瘤患者的治疗效果.外泌体与乳腺癌临床分期及预后的关系密切,在乳腺癌早期诊断和生物治疗中具有潜在的临床应用价值,可为乳腺癌的治疗提供新的希望.
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| 关 键 词： | 乳腺肿瘤 肿瘤转移 外泌体 |
Mechanism of exosome in the pathogenesis of breast cancer |
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| Abstract: | Researches show that exosome can take park in the development and progression of breast cancer by means of mediating the intercellular communication,which can promote cancer metastasis and drug resistance,thus influencing the treatment effect of patients with cancers.Exosome is closely related with clinical stage and prognosis of breast cancer,which has a potential value in the early diagnosis and biological therapy of breast cancer and provides a new hope for the treatment of breast cancer. |
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| Keywords: | Breast neoplasms Neoplasm metastasis Exosomes |
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