复方丹参-黄芪注射液治疗慢性心力衰竭

目的:观察复方丹参注射液联合黄芪治疗慢性心力衰竭的临床疗效。方法:将84例慢性心力衰竭患者随机分为治疗组和对照组,两组均给予西医综合治疗,治疗组在此基础上加用复方丹参注射液联合黄芪注射液静脉滴注辅助治疗。治疗前后记录临床症状、左心室功能、血压及心率变化情况、测定6 min步行距离。结果:治疗组的显效率和总有效率都显著优于对照组(P<0.05),两组治疗后6 min步行距离和左心室收缩末期容积、左心室舒张末期容积、左心室射血分数、血压及心率均较治疗前明显改善(P<0.05),治疗组治疗后各项指标的改善要优于对照组(P<0.05)。结论:复方丹参注射液联合黄芪能明显改善慢性心力衰竭患者的心功能,对慢性心力衰竭的治疗及预后均有良好作用,临床疗效确切。

Clinical Observation of Therapeutic Effect of Danshen and Huangqi Injection in Treatment of Chronic Heart Failure

Objective: To observe the therapeutic effect of Danshen and Huangqi injection in treatment of chronic heart failure. Method: Eighty-four patients were randomly divided into two groups. The treatment group and the control group were treated with the same routine medicine, while the treated group was additionally treated with Danshen and Huangqi. The clinical efficacy before and after treatment and the changes of color doppler ultrasonic cardiogram examinations were both observed. And walking distance in 6 minutes was detected. Result: The apparent efficiency, the total effective rate and walking distance in 6 minutes in the treated group were remarkably better than that in the control group(P<0.05). The walking distance in 6 minutes and the rate of left ventricle eject fraction (LVEF), left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), blood pressure and heart rate of the two groups were obviously improved after treatment (P<0.05). Each indexes in the treatment group were improved more than that of the control group (P<0.05). Conclusion: Danshen and Huangqi injection is an effective and safe treatment with less side effect.