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Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup
Affiliation:1. University of California, San Francisco, Department of Dermatology, San Francisco, CA 94143, USA;2. University of California, San Francisco, Biomedical Sciences Graduate Program, San Francisco, CA 94143, USA;3. University of California, San Francisco, Oral and Craniofacial Sciences Graduate Program, San Francisco, CA 94143, USA;4. University of California, Los Angeles, Department of Infectious Diseases, Los Angeles, CA 90095, USA;5. Department of Dermatology, Meyer Cancer Center, Englander Institute for Precision Medicine, Weill Cornell Medical College, New York, NY, USA;6. Immunology and Microbial Pathogenesis Program, Weill Cornell Medical College, New York, NY, USA;7. Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103, USA;8. Center for Immunity and Inflammation, Rutgers New Jersey Medical School, Newark, NJ 07103, USA
Abstract:
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  • Keywords:neonatal immunity  tolerance  skin  dendritic cells  regulatory T cells  commensal bacteria  commensals  early-life immunity  retinoic acid
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