| 狼毒属植物化学成分及药理活性研究进展 |
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| 引用本文： | 叶云云,韩璐,魏萍,苏国柱,苏田田,白长财.狼毒属植物化学成分及药理活性研究进展[J].中国中药杂志,2015,40(22):4324-4332. |
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| 作者姓名： | 叶云云 韩璐 魏萍 苏国柱 苏田田 白长财 |
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| 作者单位： | 宁夏医科大学药学院宁夏回药现代化工程技术研究中心, 宁夏银川 750004;北京中医药大学中药现代研究中心, 北京 100029,宁夏医科大学药学院宁夏回药现代化工程技术研究中心, 宁夏银川 750004,中国人民解放军 63870部队医院, 陕西华阴 714200,北京中医药大学中药现代研究中心, 北京 100029,宁夏医科大学药学院宁夏回药现代化工程技术研究中心, 宁夏银川 750004,宁夏医科大学药学院宁夏回药现代化工程技术研究中心, 宁夏银川 750004 |
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| 基金项目： | 国家"十二五"科技支撑计划项目(2013BAI11B07);国家自然科学基金项目(300020405) |
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| 摘 要： | 近年来,国内外学者对瑞香科Thymelaeaceae狼毒属Stellera植物的化学成分及药理活性进行了较为深入的研究,发现该属植物的化学成分主要包括萜类、香豆素、黄酮、木脂素及挥发油等化合物;药理学研究表明狼毒属植物中二萜及双黄酮成分具有抗肿瘤、抗HIV病毒以及免疫调节等方面的活性。该文对狼毒属植物的化学成分及药理活性方面的研究进行了系统综述,以期为该属植物活性物质的深入研究、药用价值的提升及其综合开发利用提供科学依据。
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| 关 键 词： | 狼毒属 化学成分 生物活性 综述 进展 |
| 收稿时间： | 2015/7/13 0:00:00 |
Advances on chemical constituents and bioactivities of genus Stellera |
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| YE Yun-yun,HAN Lu,WEI Ping,SU Guo-zhu,SU Tian-tian and BAI Chang-cai.Advances on chemical constituents and bioactivities of genus Stellera[J].China Journal of Chinese Materia Medica,2015,40(22):4324-4332. |
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| Authors: | YE Yun-yun HAN Lu WEI Ping SU Guo-zhu SU Tian-tian and BAI Chang-cai |
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| Institution: | Pharmaceutical School of Ningxia Medical University, Ningxia Engineering & Technology Research Center for Modernization of Hui Medicine, Yinchuan 750004, China;Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China,Pharmaceutical School of Ningxia Medical University, Ningxia Engineering & Technology Research Center for Modernization of Hui Medicine, Yinchuan 750004, China,People's Liberation Army 63870 Hospital, Huayin 714200, China,Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China,Pharmaceutical School of Ningxia Medical University, Ningxia Engineering & Technology Research Center for Modernization of Hui Medicine, Yinchuan 750004, China and Pharmaceutical School of Ningxia Medical University, Ningxia Engineering & Technology Research Center for Modernization of Hui Medicine, Yinchuan 750004, China |
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| Abstract: | Advance on chemical constituents and pharmacological activities of Stellera plants have been conducted. The chemical constituents include terpenes, coumarins, flavonoids, lignans, volatile oils, and other compounds. Pharmacological studies showed that diterpenoids and biflavones showed strong activities, such as antitumor, anti-HIV, and immune regulations. This review hopes to provide a scientific basis for further research and explorations of the medicinal values of the genus. |
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| Keywords: | Stellera chemical constituents biological activity review advances |
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