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清胰汤治疗重症急性胰腺炎的临床疗效的Meta分析
引用本文:李磊,刘静,秦侃. 清胰汤治疗重症急性胰腺炎的临床疗效的Meta分析[J]. 中国实验方剂学杂志, 2015, 21(23): 207-211
作者姓名:李磊  刘静  秦侃
作者单位:安徽医科大学第三附属医院, 合肥 230061,安徽医科大学第三附属医院, 合肥 230061,安徽医科大学第三附属医院, 合肥 230061
基金项目:安徽省"十二五"重点培育专科项目(皖卫科[2012]55号)
摘    要:
目的:系统评价清胰汤辅助治疗重症急性胰腺炎的临床疗效。方法:采用Meta分析方法,制定原始文献的纳入标准、排除标准及检索策略,计算机检索中国知网(1979—2014年),万方数据知识服务平台(1990—2014年),中国生物医学文献数据库(1978—2014),pubmed(1966—2014)等中英文数据库,按照Cochrane评价标准评价文献质量。结果:共纳入19项研究。清胰汤辅助治疗组首次排便时间[WMD=-2.098,95%CI(-2.739,-1.456),P0.01)],腹痛缓解时间[WMD=-3.008,95%CI(-3.689,-2.326),P0.01],住院时间[WMD=-7.633,95%CI(-8.449,-6.756),P0.01],病死率[OR=2.719,95%CI(1.717,4.306),P0.01]均优于对照组,有统计学意义。结论:清胰汤辅助治疗重症急性胰腺炎可显著降低患者病死率,并可缩短患者首次排便时间、腹痛缓解时间及住院时间。

关 键 词:清胰汤  重症急性胰腺炎  Meta分析
收稿时间:2015-02-12

Meta-analysis of Effectiveness of Qingyi Decoction in Treatment of Severe Acute Pancreatitis
LI Lei,LIU Jing and QIN Kan. Meta-analysis of Effectiveness of Qingyi Decoction in Treatment of Severe Acute Pancreatitis[J]. China Journal of Experimental Traditional Medical Formulae, 2015, 21(23): 207-211
Authors:LI Lei  LIU Jing  QIN Kan
Affiliation:The Third Affiliated Hospital of Anhui Medical University, Hefei 230061, China,The Third Affiliated Hospital of Anhui Medical University, Hefei 230061, China and The Third Affiliated Hospital of Anhui Medical University, Hefei 230061, China
Abstract:
Objective: To evaluate the effectiveness of Qingyi decoction in the treatment of severe acute panereatitis in a systematic review. Method: The inclusion and exclusion criteria and retrieval strategies were made using Meta-analysis methods, with computer retrieval of CNKI (1979-2014), Wanfang Data Knowledge Service Platform (1990-2014), Chinese Biomedical Database (1978-2014), pubmed (1966-2014) and other Chinese and English databases.The quality of the literatures was assessed according to Cochrane review criteria. Result: The 19 studies were included. Compared with control group, the adjunctive therapy with Qingyi decoction group had significant differences in the time of first defecation[WMD=-2.098, 95%CI(-2.739,-1.456), P<0.01)], the time of stomach ache relief[WMD=-3.008, 95%CI(-3.689,-2.326), P<0.01], hospital stay (days)[WMD=-7.633, 95%CI(-8.449,-6.756), P<0.01], case fatality rate[OR=2.719, 95%CI (1.717, 4.306), P<0.01]. Conclusion: The adjunctive therapy with Qingyi decoction in severe acute pancreatitis can significantly decrease the case fatality rate, shorten the first time of defecation, stomachache relief time and hospital stay.
Keywords:Qingyi decoction  severe acute panereatitis  Meta-analysis
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