马来酸桂哌齐特治疗短暂性脑缺血的临床疗效观察

目的探讨马来酸桂哌齐特在短暂性脑缺血发作方面的临床疗效。方法将80例短暂性脑缺血患者随机分为两组，观察组和对照组各40例。观察组患者静脉滴注马来酸桂哌齐特，对照组患者静脉滴注血栓通注射液，对两组患者治疗后的短暂性脑缺血发作停止时间、例数以及治疗前后的血液流变学变化、血常规、尿常规、肝肾功能以及副反应进行观察和比较。结果观察组患者24h内短暂性脑出血发作控制率和总有效率分别为62．5％和95．0％，显著高于对照组（P〈0．05）；观察组患者治疗后的血液黏度以及血小板黏附率显著低于治疗前和对照组治疗后（P〈0．05）；两组间副反应发生率分别为12．5％和15．0％，差异无统计学意义（P〉0．05）。结论马来酸桂哌齐特治疗短暂性脑缺血发作能有效改善患者血流动力学变化，疗效显著且无严重不良反应发生，值得临床推广。

The observation of the clinical effect for maleate cinepazide in the treatment of transient ischemic

Objective To investigate the clinical efficacy for maleate cinepazide in the treatment of transient ischemic. Methods Eighty cases of transient ischemic patients were randomly divided into two groups, the observation group and the control group, and 40 cases in each. The observation group was taken with intravenously maleate gui donepezil special, and the control group was taken with intravenous infusion Xueshuantong injection. The transient cerebral ischemic attack stop time hemorheological changes in the number of cases as well as before and after treatment, blood routine, urine routine, liver and kidney function, and adverse events for the two groups of patients after treatment were observed and compared. Results The transient cerebral bleeding episodes control rate and total efficiency rate were 62.5% and 95.0% in the observation group patients within 24 hours, significantly higher than the control group （P 〈 0.05）. The blood viscosity and platelet adhesion rate in patients after treatment were significantly lower than before treatment and control group after treatment （P 〈 0.05）. The incidence of side effects were 12.5% and 15.0% for the two groups, the difference was not statistically significant （P 〉 0.05）. Conclusion The maleate, cinepazide in the treatment of transient ischemic attack can effectively improve the hemodynamic changes in patients, there is significant effect and without serious adverse reactions occurred, and it is worthy of promotion.