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| 骨髓间充质干细胞在视网膜移植领域的研究进展 | |
| 引用本文： | 徐志刚,吕淑慧,穆敬中,张雪岩,齐艳秀,朱金玲. 骨髓间充质干细胞在视网膜移植领域的研究进展[J]. 国际眼科杂志, 2013, 13(1): 79-81 |
| 作者姓名： | 徐志刚 吕淑慧 穆敬中 张雪岩 齐艳秀 朱金玲 |
| 作者单位： | 中国黑龙江省佳木斯市,佳木斯大学附属第一医院眼科;中国黑龙江省佳木斯市,佳木斯大学附属第一医院眼科;中国黑龙江省佳木斯市,佳木斯大学附属第一医院眼科;中国黑龙江省佳木斯市,佳木斯大学附属第一医院眼科;中国黑龙江省佳木斯市,佳木斯大学附属第一医院眼科;中国黑龙江省佳木斯市,佳木斯大学附属第一医院眼科 |
| 基金项目： | 黑龙江省教育厅科学技术研究项目(No.12521530) |
| 摘 要： | 临床上对于视网膜退行性疾病的治疗仍然只停留在改善循环、营养神经等支持治疗阶段,缺少特效的治疗方法,骨髓间充质干细胞(bone mesenchymal stem cells,BMSCs)是具有较强自我复制功能和多向分化潜能的一类细胞,人们开始通过尝试不同的分离、诱导、移植等手段,以实现其向视网膜细胞的转化,并最终实现体内的替代治疗。我们就BMSCs在视网膜移植领域的研究进展进行综述,以期为进一步的研究提供参考。 |
| 关 键 词： | 骨髓间充质干细胞 视网膜神经样细胞 光感受器样细胞 |
| 收稿时间： | 2012-10-16 |
| 修稿时间： | 2012-12-17 |
Research progress of bone marrow mesenchymal stem cells applied to the retina transplantation photoreceptor-like cell |
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| Zhi-Gang Xu,Shu-Hui Lü,Jing-Zhong Mu,Xue-Yan Zhang,Yan-Xiu Qi,Jin-Ling Zhu. Research progress of bone marrow mesenchymal stem cells applied to the retina transplantation photoreceptor-like cell[J]. International Eye Science, 2013, 13(1): 79-81 | |
| Authors: | Zhi-Gang Xu Shu-Hui Lü Jing-Zhong Mu Xue-Yan Zhang Yan-Xiu Qi Jin-Ling Zhu |
| Affiliation: | Department of Ophthalmology, the First Affiliated Hospital of Jia Mu Si University, Jiamusi 154002, Heilongjiang Province, China;Department of Ophthalmology, the First Affiliated Hospital of Jia Mu Si University, Jiamusi 154002, Heilongjiang Province, China;Department of Ophthalmology, the First Affiliated Hospital of Jia Mu Si University, Jiamusi 154002, Heilongjiang Province, China;Department of Ophthalmology, the First Affiliated Hospital of Jia Mu Si University, Jiamusi 154002, Heilongjiang Province, China;Department of Ophthalmology, the First Affiliated Hospital of Jia Mu Si University, Jiamusi 154002, Heilongjiang Province, China;Department of Ophthalmology, the First Affiliated Hospital of Jia Mu Si University, Jiamusi 154002, Heilongjiang Province, China |
| Abstract: | Nowadays, treatments for retinal degenerative diseases mainly stay in supportive treatments such as improve circulation, nourishing nerve in the clinical. It still lacks effective treatment. As bone marrow mesenchymal stem cells(BMSCs)have high expansion potential and autologous immunological characteristics,people have tried various ways of isolation, induction, transplantation and so on,with a purpose to transform BMSCs to retinal nerve cells,and ultimately make cell-replaced therapy available. We reviewed the current literature for trials and case reports on retina transplantation of BMSCs, to provide help for the further research. |
| Keywords: | bone marrow mesenchymal stem cells retinal nerve-like cells photoreceptor-like cell |
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