LASIK术后干眼症研究

目的:研究LASIK术后干眼症的发病率在高度近视人群和低度近视人群之间的差异性以及探讨预防的方法与机制。方法:这项研究是基于对2010-05/2011-05在武汉市爱尔眼科医院接受LASIK手术388例患者的回顾性分析。患者被区分为高度近视和低度近视,数据包括干眼症状、泪液量、泪液分泌、泪膜稳定性、角膜上皮缺损等,分析采用SPSS15.0统计学软件。结果:LASIK术后高度近视患者中干眼症症状的发病率明显高于低度近视人群,高度近视患者在LASIK手术前和手术后的各个观察时间段的泪液量较低,泪膜稳定性较差,术后患干眼症症状的比率显著高于低度近视患者。结论:无论是高度近视人群还是低度近视人群,女性患干眼症的比率明显高于男性。LASIK术后高度近视患者患干眼症的几率明显高于低度近视患者,而且高度近视患者比低度近视患者在术后患干眼症的症状更严重,更持久,治疗恢复时间也更长。预防和处置LASIK术后干眼症的发病几率要重在术前检查筛选,提前治疗干预。对于高度近视患者,要尽可能选择ICL或TICL手术来进行屈光矫正。

Research of xerophthalmia after LASIK

AIM: To study the incidence of xerophthalmia between people with high myopia and low myopia after laser in situ keratomileusis(LASIK), and find a way to prevent the xerophthalmia.

METHODS: The research was based on the retrospective analysis of 388 patients who underwent LASIK surgery in Wuhan Aier Eye Hospital during the 2010-2011. The Patients were divided into low and high myopia group. Assessment included xerophthalmia symptoms, tear fluid quantity, lacrimal secretion, tear film stability, corneal epithelial defect and corneal sensation, etc.

RESULTS: After the surgery, patients with high myopia were significantly higher than the incidence of low myopia groups. High myopia patients, who underwent the LASIK, would have lower tear volume, poorer tear film stability, and higher rate to suffer xerophthalmia symptoms than that of low myopia patients during the observation periods before or after the surgery.

CONCLUSION: Both low and high myopia groups, the rate of women suffering from dry eye was significantly higher than men. Patients with high myopia was significantly higher than the risk of suffering from dry eye syndrome in patients with low myopia, and high myopia than low myopia patients suffering from dry eye symptoms after LASIK is more severe and more lasting. For patients with high myopia, ICL or TICL surgery should be chosen as possible to for refractive correction.