| 帕罗西汀与阿米替林治疗抑郁症对照研究 |
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| 引用本文： | 胡水亭,李涛,李小杰. 帕罗西汀与阿米替林治疗抑郁症对照研究[J]. 中国民康医学, 2007, 19(17): 744-745 |
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| 作者姓名： | 胡水亭 李涛 李小杰 |
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| 作者单位： | 河南省许昌市建安医院精神科,河南,许昌,461000 |
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| 摘 要： | 目的：探索帕罗西汀与阿米替林治疗抑郁症的疗效与安全性。方法：选定58例符合CCMD-3诊断标准的抑郁症患者随机分为两组,分别给予帕罗西汀与阿米替林治疗8周,用汉密尔顿抑郁量表（HAMD）评定临床疗效,用副反应量表（TESS）评定不良反应。结果：两组治疗抑郁症的疗效基本近似,帕罗西汀较阿米替林起效快,不良反应轻。结论：帕罗西汀治疗抑郁症疗效好,不良反应轻。
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| 关 键 词： | 帕罗西汀 阿米替林 抑郁症 |
| 文章编号： | 0369（2007）09-0744-02 |
| 修稿时间： | 2007-01-26 |
A controlled study on the treatment of depression with paroxetine and amitriptyline |
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| HU Shui-ting,LI Tao,LI Xiao-jie. A controlled study on the treatment of depression with paroxetine and amitriptyline[J]. medical journal of chinese peoples health, 2007, 19(17): 744-745 |
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| Authors: | HU Shui-ting LI Tao LI Xiao-jie |
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| Affiliation: | Department of Psychiatry ,JIANAN Hospital of Xuchang City ,Henan 461000 ,China |
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| Abstract: | Objective: To explore the efficacy and side effect of paroxetine and amitriptyline.Methods:58 patients who met CCMD-3 criterion for depression episode were randomly assigned to paroxetine group(n=30) and amitriptyline group(n=28) for the treatment of 8 weeks.The clinical efficacy was evaluated by HAMD.The side effects were evaluated by TESS.Results: There was no significant difference of the efficacy between two groups.Paroxetine showed rapider efficacy and less side effects than amitriptyline.Conclusions: Paroxetine showed sure efficacy and less side effects. |
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| Keywords: | Paroxetine Amitriptyline Depression |
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