| 冠心病患者红细胞体积分布宽度变化及其临床意义 |
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| 引用本文： | 黄媛,陈建魁,于农,宋世平,尹秀云,金欣,杜宇.冠心病患者红细胞体积分布宽度变化及其临床意义[J].临床误诊误治,2011,24(10):12-14. |
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| 作者姓名： | 黄媛 陈建魁 于农 宋世平 尹秀云 金欣 杜宇 |
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| 作者单位： | 军事医学科学院附属医院检验科,北京,100071 |
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| 摘 要： | 目的观察冠心病患者红细胞体积分布宽度(RDW)的变化,探讨其临床应用价值。方法选择我院2008年1月～2010年10月冠心病515例,随机分为心绞痛组365例,急性心肌梗死(AMI)组103例,急性心力衰竭(AHF)组47例,并选取同期健康体检430例作为对照组。均检测血红蛋白(Hb)、RDW、超敏C反应蛋白(hs-CRP)、B型脑钠肽(BNP)并进行比较。结果 515例冠心病RDW水平较对照组明显增高,差异有统计学意义(P<0.01);AHF组RDW水平较心绞痛组增高,差异有统计学意义(P<0.05);按照RDW四分位数分组,随着RDW的逐级增高,AMI、AHF的发病率逐级增高,冠心病患者病死率也逐级增高;RDW与BNP呈正相关(r=0.415,P<0.01),与hs-CRP亦呈正相关(r=0.234,P<0.01),但相关性较弱。结论 RDW可能为冠心病患者预后的独立预测因子,有助于判断冠心病患者的预后。
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| 关 键 词： | 冠状动脉疾病 红细胞体积分布宽度 利钠肽 脑 C反应蛋白 预后 判断 |
The Changes and Clinical Application Value of Red Blood Cell Distribution Width in Patients with Coronary Heart Disease |
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| HUANG Yuan,CHEN Jian-kui,YU Nong,SONG Shi-ping,YIN Xiu-yun,JIN Xin,DU Yu.The Changes and Clinical Application Value of Red Blood Cell Distribution Width in Patients with Coronary Heart Disease[J].Clinical Misdiagnosis & Mistherapy,2011,24(10):12-14. |
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| Authors: | HUANG Yuan CHEN Jian-kui YU Nong SONG Shi-ping YIN Xiu-yun JIN Xin DU Yu |
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| Institution: | HUANG Yuan,CHEN Jian-kui,YU Nong,SONG Shi-ping,YIN Xiu-yun,JIN Xin,DU Yu(Affiliated Hospital of Academy of Military Medical Sciences,Beijing 100071,China) |
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| Abstract: | Objective To observe the changes of red blood cell distribution width(RDW) in patients with coronary heart disease(CHD) and to evaluate its clinical application value.Methods 515 patients with CHD admitted into our hospital were enrolled and divided into angina pectoris group(n=365),acute myocardial infarction(AMI) group(n=103) and acute heart failure(AHF) group(n=47),and 430 healthy controls were selected as control group.The levels of Hemoglobin(Hb),RDW,High-sensitive C-reaction protein(hs-CRP) and B-type... |
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| Keywords: | Coronary artery disease Red blood cell distribution width natriuretic peptide brain C-reaction protein Prognosis Judgment |
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