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| 尖锐湿疣病人外周血及病变局部T淋巴细胞亚群的研究 | |
| 引用本文： | 郑华 孙宝符. 尖锐湿疣病人外周血及病变局部T淋巴细胞亚群的研究[J]. 中国皮肤性病学杂志, 1993, 7(3): 144-145 |
| 作者姓名： | 郑华 孙宝符 |
| 作者单位： | 白求恩医科大学第一临床医学院皮肤科 130021(郑华)，白求恩医科大学第一临床医学院皮肤科 130021(孙宝符) |
| 摘 要： | 采用APAAP技术对34例尖锐湿疣(CA)病人外周血及病变局部T淋巴细胞亚群进行了免疫组化研究,结果表明:CA病人外周血中CD_8~+细胞百分比升高,CD_4~+/CD_8~+比率下降,显示病人机体内存在细胞免疫缺陷。病变局部皮肤粘膜中CD_8~+细胞升高及CD_4~+/CD_8~+比率下降,提示病人存在局部细胞免疫障碍。 |
| 关 键 词： | 尖锐湿疣 T淋巴细胞 抗体,单克隆 碱性磷酸酶-抗碱性磷酸酶技术(APAAP) |
A study on T Lymphocyte Subpopulations in Peripheral Blood and Skin and Mucous Membrance Local Lesions in 34 Cases with Condyloma Acuminata. |
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| Zheng Hua,Sun Baofu. A study on T Lymphocyte Subpopulations in Peripheral Blood and Skin and Mucous Membrance Local Lesions in 34 Cases with Condyloma Acuminata.[J]. The Chinese Journal of Dermatovenereology, 1993, 7(3): 144-145 | |
| Authors: | Zheng Hua Sun Baofu |
| Affiliation: | Zheng Hua,Sun Baofu. Department of Dermatology,Firstty Teaching Hospital,Norman Bethune University of Medical Sciences,Changchun. |
| Abstract: | T lymphocyte subpopulations in peripheral blood and skin, mucous membrane local lesions in 34 cases with condyloma acuminata were studied by using alkaline phosphatase anti-alkaline phosphatase (APAAP) method, the results showed that both in peripheral blood and in local lesions, the CD8~+ cell increased, and the rate of CD4~+/CD8~+ decreased. It was suggested that might be a cellular immunological defect in CA patients. |
| Keywords: | condyloma acuminata T lymphoantibodies monoclonal |
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