沈阳市孕妇弓形虫感染的临床研究

目的：探讨孕妇弓形虫（TOX）感染的状况及感染后对其胎儿的影响。方法：用酶联免疫吸附试验（ELISA）法检测孕妇血中弓形虫循环抗原（CAg）、IgG及IgM抗体。结果：93例病理妊娠的孕、产妇血清中CAg阳性者19例（20．43％），TOX—IgG阳性者21例（22．58％）及TOX—IgM阳性者9例（9．68％）。而93例正常产孕妇血清中CAg阳性者仅为2例（2．15％），TOX—IgG阳性者3例（3．23％）及TOX-IgM阳性者1例（1．08％）。结论：TOX感染对胎儿有较大的危害，是引起胎儿流产、死产死胎和畸形的主要原因之一。因此，孕妇妊娠早期应进行弓形虫感染检测，感染者应进行治疴。

Clinical Study of toxoplasma Infection in Pregnant Women in Shenyang

Objective： To investigate the status of toxoplasma （TOX） infection in pregnant women and the effect of TOX infection during pregnancy to the development of fetus. Methods： Enzyme linked immunoabsorbent assay （ELISA） was employed to detect TOX-IgG, TOX-IgM and CAg in peripheral blood of pregnant women. Results： Among 93 cases with the abnormal pregnancy, 21 cases were TOX-IgG positive （22.58%） , 9 cases were TOX-IgM positive （968 % ） and 19 cases were CAg positive （20. 43% ）. In normal pregnant group, 3 cases were TOX-IgG positive （3.23%）, 1 case was TOX-IgM positive （1.08%） and 2 cases CAg were positive （2. 15% ）. Condusion： TOX infection is great harmful to fetus and important factor leading to abortion, stillbirth and malformation. In early pregnancy, pregnant women should be detected for TOX infection and the infective women should be treated.