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| 甲亢宁对甲亢大鼠甲状腺激素及心钠素的影响 | |
| 引用本文： | 林兰,李鸣镝,刘喜明,楚晓燕,王兆礼. 甲亢宁对甲亢大鼠甲状腺激素及心钠素的影响[J]. 中国中医基础医学杂志, 2005, 11(1): 34-35,60 |
| 作者姓名： | 林兰 李鸣镝 刘喜明 楚晓燕 王兆礼 |
| 作者单位： | 中国中医研究院,广安门医院,北京,100053 |
| 基金项目： | 国家中医药管理局科研项目 |
| 摘 要： | 目的:观察中药甲亢宁胶囊对甲亢大鼠模型的治疗作用.方法:用甲状腺素片饲服的方法制作大鼠甲亢模型,将大鼠随机分成7组:正常对照组、空白对照组、甲亢宁3.0g/kg组、甲亢宁1.5g/kg组、甲亢宁0.75g/kg组、甲亢宁加他巴唑1.25mg/kg组和他巴唑组,14d后测定血清三碘甲腺原氨酸(T3)、甲状腺素(T4)、促甲状腺激素(TSH)含量及血浆心钠素(ANP)水平.结果:甲亢宁能降低甲亢大鼠血清T3、T4含量及血浆ANP水平,提高血清TSH水平,对其体重降低有一定抑制作用.结论:甲亢宁胶囊能有效降低实验性甲亢大鼠的甲状腺激素和心钠素水平. |
| 关 键 词： | 甲亢大鼠模型 甲亢宁胶囊 甲状腺激素 心钠素 |
| 文章编号： | 1006-3250(2005)01-0034-02 |
Effect of Traditional Chinese Medicine JiaKangNing capsule on Thyroid and ANP of Hyperthyroid rats |
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| LIN Lan,LI Ming di,LIU Xi ming,CHU Xiao yan,WANG Zhao li. Effect of Traditional Chinese Medicine JiaKangNing capsule on Thyroid and ANP of Hyperthyroid rats[J]. Chinese Journal of Basic Medicine In Traditional Chinese Medicine, 2005, 11(1): 34-35,60 | |
| Authors: | LIN Lan LI Ming di LIU Xi ming CHU Xiao yan WANG Zhao li |
| Abstract: | Object:To evaluate the effectiveness of JiaKangNing capsule on hyperthyroid rats.Methods:After prepared as the model of hyperthyroid rats by using thyroid tab,the rats were randomized to seven groups:The normal rats group,the control group,the JiaKangNing suspension 3.0g/kg,1.5g/kg,0.75g/kg groups respectively,the JiaKangNing plus MMI 1.25mg/kg group,the MMI group.After 14 days the rats' serum T 3,T 4,TSH and plasma ANP were examined.Results:The serum T 3,T 4 and plasma ANP of hyperthyroid rats is lowered by JiaKangNing,and JiaKangNing can reduce the weight of rats.Conclusion:JiaKangNing capsule can effectively reduce the thyroid and ANP of hyperthyroid rats. |
| Keywords: | JiaKangNing capsule thyroid ANP |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |