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宫颈癌调强放疗应用的剂量特点探讨
引用本文:余娴,王阁,杨晓霞,杨镇洲,刘岩海,马俊刚. 宫颈癌调强放疗应用的剂量特点探讨[J]. 陕西肿瘤医学, 2009, 17(12): 2410-2413
作者姓名:余娴  王阁  杨晓霞  杨镇洲  刘岩海  马俊刚
作者单位:第三军医大学大坪医院野战外科研究所肿瘤中心,重庆400042
摘    要:
目的:分析10例宫颈癌调强放疗(IMRT)与箱式四野放疗各危及器官剂量差别和急性毒副反应,评价IMRT做为宫颈癌常规放疗的可行性。方法:选择2006年1月至2007年3月我科收治的10例宫颈癌根治性放疗患者,每位患者均同时作调强计划和箱氏四野计划,比较各危及器官的DVH曲线图。结果:两种方法处方剂量均较好的覆盖了靶区。在50Gy水平,IMRT中小肠、膀胱、直肠的体积分别减少了24.1%、38.1%、28.5%,患者副反应轻微,治疗过程中患者耐受性好。结论:IMRT在宫颈癌治疗中剂量分布优于箱式四野放疗。

关 键 词:宫颈癌  调强放疗  剂量特点

Dosimetric characteristic for cervical cancer patients receiving intensity modulated Radiation therapy
Affiliation:YU Xian, WANG Ge, YANG Xiao - xia, YANG Zhen - zhou, LIU Yah - hai, MA Jun - gang (Cancer Center, Daping Hospital of Third Military Medical University, Chongqing 400042, China.)
Abstract:
Objective :To analysis the impact difference between the IMRE and box fieldwork between organ dose and acute toxic reaction of 10 cases of cervical cancer. Methods :Ten cervical cancer patients treated with radical radiotherapy were selected and do the planning of IMRT and box fieldwork for each of patient , the compare DVH cure to oberve the endanger organ. Results: The prescrption does of the two methods showed good coverage of target at 50 Gy,for IMRT,the volume of small intestine ,bladder,rectal decreased by 24.1% ,38.1% ,and 28.5%. Patients had less side effects , and well tolerated. Conclusion: IMRT has more advantages than four fields box of types in teletherapy with cervical carcinoma.
Keywords:cervical cancer IMRT    dosimetric characteristic
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