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胃肠道间质瘤的诊断与治疗
引用本文:张兴龙,吴育连.胃肠道间质瘤的诊断与治疗[J].中国中西医结合外科杂志,2010,16(6):633-635.
作者姓名:张兴龙  吴育连
作者单位:[1]浙江省开化县人民医院外科,开化324300 [2]浙江大学医学院附属第二医院外科,杭州310009
摘    要:目的:总结胃肠道间质瘤的诊断与治疗方法。方法:回顾性分析93例胃肠道间质瘤临床资料。结果:临床表现主要为腹痛、腹胀,上腹部不适,以CT、MRI为主要影像学检查。全部行手术治疗,免疫组化示CD117及CD34阳性率达95.7%和62.4%,术后1、3、5年生存率分别为94.2%、85.2%和78.2%。结论:胃肠道间质瘤无特异性临床表现,治疗以手术切除为主;对于无法手术切除者,伊马替尼治疗具有一定效果。

关 键 词:胃肠道间质瘤  诊断  治疗

Diagnosis and Treatment of Gastrointestinal Stromal Tumors
Zhang Xinglong,Wu Yulian.Diagnosis and Treatment of Gastrointestinal Stromal Tumors[J].Chinese Journal of Surgery of Integrated Traditional and Western Medicine,2010,16(6):633-635.
Authors:Zhang Xinglong  Wu Yulian
Institution:Department of Surgery, People’s Hospital, Kaihua Country, Zhejing Province,Kaihua (324300), China
Abstract:objective To summarize the diagnosis and treatment of gastrointestinal stromal tumors(GIST) Methods The clinical data of 93 cases of GIST (2000-2009)were retrospectively analyzed. Results Abdominal pain and upper abdominal malaise were present in most patients, CT and MRI were good methods for diagnosis. All of the 93 patients received surgical treatment. The positive immunohistochemical rate of CD117 and CD34 was respectively 95.7% and 62.4%. The 1-year, 3-year and 5-year survival rate was 94.2%, 85.2% and 78.2% respectively. Conclusion Surgical treatment is the most effective method, as to unresectable tumor, imatinib mesylate is effective
Keywords:gastrointestinal stromal tumors  diagnosis  treatment
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