| Survivin,VEGF及MVD在尖锐湿疣组织中的表达 |
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| 引用本文： | 李敏,尹光文,李旭阳,李孝辉. Survivin,VEGF及MVD在尖锐湿疣组织中的表达[J]. 中国皮肤性病学杂志, 2011, 25(9): 664-666 |
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| 作者姓名： | 李敏 尹光文 李旭阳 李孝辉 |
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| 作者单位： | 1. 河南省人民医院皮肤科,河南,郑州,450003
2. 郑州大学第一附属医院,河南郑州,450052 |
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| 基金项目： | 河南省科技创新杰出青年基金,河南省重点科技攻关项目 |
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| 摘 要： | 目的 观察尖锐湿疣(CA)组织中Survivin和血管内皮生长因子(VEGF)的表达及微血管密度(mi-crovessel density,MVD)的分布情况.方法 采用免疫组化法检测48例尖锐湿疣组织和25例正常包皮组织中Survivin,VEGF及CD34的表达.用CD34单克隆抗体进行微血管内皮细胞染色,计算MV...
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| 关 键 词： | Survivin 血管内皮生长因子 微血管密度 尖锐湿疣 |
The Expression of Survivin, VEGF and MVD in CA Tissues |
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| LI Min,YIN Guang-wen,LI Xu-yang,LI Xiao-hui. The Expression of Survivin, VEGF and MVD in CA Tissues[J]. The Chinese Journal of Dermatovenereology, 2011, 25(9): 664-666 |
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| Authors: | LI Min YIN Guang-wen LI Xu-yang LI Xiao-hui |
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| Affiliation: | LI Min*,YIN Guang-wen,LI Xu-yang,LI Xiao-hui(The First Affiliate Hospital of Zhengzhou University,Zhengzhou 450052,China,*Department of Dermatology,People's Hospital of Henan Provence,Zhengzhou 450003,China) |
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| Abstract: | Objective To explore the expression of Survivin,vascular endothelial cell growth factor(VEGF),and the distribution of microvessel density(MVD)in lesions of Condyloma Acuminatum(CA).Methods The expression of Survivin,VEGF,and CD34 were examined by immunohistochemical staining in lesions of CA in 48 cases and 25 normal foreskins,MVD was calculated by using monoclonal antibodies for CD34 microvascular endothelial cells staining.Results The positive rate of Survivin and VEGF in CA tissues was 68.75%(33/48) and ... |
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| Keywords: | Survivin |
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