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绿衣枳实的化学成分
引用本文:余平,梁敬钰,刘鑫.绿衣枳实的化学成分[J].中国天然药物,2010(2):97-100.
作者姓名:余平  梁敬钰  刘鑫
作者单位:中国药科大学天然药物化学教研室;
摘    要:目的:研究绿衣枳实(Poncirus trifoliata(L.)Raf.)的化学成分。方法:对绿衣枳实95%乙醇提取物的氯仿部分进行色谱分离,根据光谱数据和理化性质确定各化合物的结构。结果:分离得到8个已知化合物,分别为:21α-methylmelianodiol(1),21β-methylmelianodiol(2),21α,25-dimethylmelianodiol(3),21α-methyltoosen-danpentol(4),21R,23R-epoxy-21α-methoxy-7,24,25-trihydroxy-14-apotirucallen-3-one(5),21S,23R-epoxy-21β-methoxy-7,24,25-trihydroxy-14-apotirucallen-3-one(6),21R,23R-epoxy-21α-ethoxy-24S,25-dihy-droxy-apotirucalla-7-en-3-one(7),ichanexic acid(8).。结论:化合物4-8为首次从枳属中分得。

关 键 词:绿衣枳实  三萜

Chemical Constituents from the Fruits of Poncirus trifoliata
YU Ping,LIANG Jing-Yu,LIU Xin.Chemical Constituents from the Fruits of Poncirus trifoliata[J].Chinese JOurnal of Natural Medicines,2010(2):97-100.
Authors:YU Ping  LIANG Jing-Yu  LIU Xin
Institution:YU Ping,LIANG Jing-Yu,LIU Xin Department of Natural Medicinal Chemistry,China Pharmaceutical University,Nanjing 210009,China
Abstract:AIM:To investigate the chemical constituents from the fruits of Poncirus trifoliata(L.)Raf.. METHODS:The constituents of CHCl3-soluble portions in the 95%ethanol extract were isolated and purified by various chromatographic methods.Their structures were identified by the physicochemical characteristic and spectral data. RESULTS:Eight known compounds were isolated and identified as 21α-methylmelianodiol(1),21β-methylmelianodiol(2),21α,25-dimethylmelianodiol(3),21α-methyltoosendanpentol(4),21R,23R-epoxy-21α-methoxy-7,24,25-trihydroxy-14-apotirucallen-3-one(5),21S,23R-epoxy-21β-methoxy-7,24,25-trihydroxy-14-apotirucallen-3-one(6),21R, 23R-epoxy-21α-ethoxy,24S,25-dihydroxy-apotirucalla-7-en-3-one(7),ichanexic acid(8).CONCLUSION:Compounds(4-8)were isolated from the Poncirus genus for the first time.
Keywords:Poncirus trifoliata  Triterpene  
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