| 脑梗塞病人血浆LCAT活性与脂蛋白及红细胞膜脂质含量的关系 |
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| 引用本文： | 赵仁亮,王春霞,牟晓峰,唐盛孟.脑梗塞病人血浆LCAT活性与脂蛋白及红细胞膜脂质含量的关系[J].齐鲁医学杂志,1998(1). |
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| 作者姓名： | 赵仁亮 王春霞 牟晓峰 唐盛孟 |
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| 作者单位： | 青岛医学院 |
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| 摘 要： | ①目的探讨脑梗塞病人血浆卵磷脂－胆固醇酰基转移酶（ＬＣＡＴ）活性与脂蛋白及红细胞膜脂质含量的关系，②方法应用外加底物法铡定４８例脑梗塞病人和３６例健康人血浆ＬＣＡＴ括性，并检测血浆高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）和亚组分（ＨＤＬ２－Ｃ，ＨＤＬ３－Ｃ）、低密度脂蛋白胆固醇（ＬＤＬ－Ｃ）、载脂蛋白Ａ－１和Ｂ（ａｐｏＡ－１，ａｐｏＢ）、红细胞膜胆固醇（ＲＢＣＭ－ＣＨ）和红细胞膜磷腊（ＲＢＣＭ－ＰＬ）的含量变化。③结果脑梗塞病人血浆ＬＣＡＴ活性、ＨＤＬ－Ｃ，ＨＤＬ２－Ｃ及ａｐｏＡ－１含量明显降低，血浆ＬＤＬ－Ｃ，ａｐｏＢ，ＲＢＣＭ－ＣＨ及ＲＢＣＭ－ＣＨ／ＲＢＣＭ－ＰＬ比值显著增高，与对照组比较差异有显著性（ｔ＝２．１４－３．２５，Ｐ＜０．０５，０．０１），血浆ＬＣＡＴ活性与ＨＤＬ－Ｃ，ＨＤＬ２－Ｃ及ａｐｏＡ－１呈正相关（ｒ＝０．３８４，Ｐ＜０．０１；ｒ＝０．２９８，Ｐ＜０．０５；ｒ＝０．３１９，Ｐ＜０．０５），而与ＬＤＬ－Ｃ，ＲＢＣＭ－ＣＨ呈负相关（ｒ＝－０．２９０，－０．３２３；Ｐ＜０．０５）。④结论脑梗塞病人脂质代谢异常与血浆ＬＣＡＴ活性降低有关。
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| 关 键 词： | 脑梗塞，脂蛋白类，红细胞膜，脂类，卵磷脂酰基转移酶类 |
A CORRELATIVE STUDY OF PLASMA LCAT ACTIVITY AND LIPOPROTEIN AND RED BLOOD CELL MEMBRANE LIPID COMPOSITIONS IN PATIENTS WITH CEREBRAL INFARCTION |
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| Zhao Renliang,Wang Chunxia,Mu Xiaofeng,et al De- partment of Neurology,The Affiliated Hospital of Qingdao Medical College,Qingdao.A CORRELATIVE STUDY OF PLASMA LCAT ACTIVITY AND LIPOPROTEIN AND RED BLOOD CELL MEMBRANE LIPID COMPOSITIONS IN PATIENTS WITH CEREBRAL INFARCTION[J].Medical Journal of Qilu,1998(1). |
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| Authors: | Zhao Renliang Wang Chunxia Mu Xiaofeng De- partment of Neurology The Affiliated Hospital of Qingdao Medical College Qingdao [ |
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| Institution: | Zhao Renliang,Wang Chunxia,Mu Xiaofeng,et al De- partment of Neurology,The Affiliated Hospital of Qingdao Medical College,Qingdao 266003 [ |
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| Abstract: | |
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| Keywords: | cerebral infarction lipoprotein erythrocyte membrane lipids lecithin acyltransferase |
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