颅脑损伤急性期D-二聚体的动态变化及与CT、临床的关系

目的 探讨颅脑损伤急性期D-二聚体(DD)含量的变化及与CT影像变化和临床预后的相关性.方法 动态临测87例不同伤情颅脑损伤患者和检测90例健康对照者血浆中DD含量的变化,同时行GCS、GOS评分,并与CT结果 比对.结果 颅脑损伤患者DD含量明显高于对照组,差异有统计学意义(P＜0.05);损伤患者DD检测水平与GCS、GOS呈现负相关,和CT影像变化呈正相关,并随伤情演变同步.结论 DD的定量检测与影像学变化密切相关,其有助于判断颅脑损伤患者预后.

Correlations between levels of plasma D-dimer and CT images as well as prognosis in patients with acute head injuries

Objective To study the correlations between levels of plasma D-dimer (DD) and CT images as well as prognosis of acute head injury. Methods The levels of plasma DD were quantitatively dynamically measured and CT images were taken in 87 patients with head injuries. The relationships of the concentration of DD with Glasgow coma score (GCS), Glasgow outcome score(GOS) and CT images were studied. Results The level of plasma DD in patients with bead injuries was significantly higher than that of control group (P<0.05). The concentration of DD was positively correlated with CT alterations, and negative correlated with GCS and GOS. Conclusion The level of plasma DD is correlated with change of CT images, which may be useful for judging the severity and prognosis in the early stage of head injury.