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胎脾LAK细胞加rIL-2治疗51例中晚期恶性肿瘤临床疗效观察
引用本文:王润田,姜少灏,张红中,姚树坤,周学敏,刘文虎,朱铁年. 胎脾LAK细胞加rIL-2治疗51例中晚期恶性肿瘤临床疗效观察[J]. 河北医科大学学报, 1995, 0(1)
作者姓名:王润田  姜少灏  张红中  姚树坤  周学敏  刘文虎  朱铁年
摘    要:
用胎脾LAK细胞加rIL-2治疗中晚期恶性肿瘤51例,其中CR3例,PR7例,有效率CR+PR为19.6%,CR+PR+MR为31.4%。大多数患者临床症状改善,生活质量提高,生存期延长,治疗中未见严重副反应。

关 键 词:胎脾LAK细胞,重组白细胞介素2,过继免疫治疗,肿瘤

CLINCAL OBSERVATIONS ON 51 CASES OF MALIGNANT PATIENTS AT MIDDLE AND ADVANCED STAGES TREATED WITH LAK CELLS FROM FETAL SPLENOCYTES PLUS rLL-2
Wang Runtian,Jiang Shaohao,Zhang Hongzhong,Yao ShukunZhou Xuemin,Liu Wenhu,Zhu Tienian,Wang Huifen. CLINCAL OBSERVATIONS ON 51 CASES OF MALIGNANT PATIENTS AT MIDDLE AND ADVANCED STAGES TREATED WITH LAK CELLS FROM FETAL SPLENOCYTES PLUS rLL-2[J]. Journal of Hebei Medical University, 1995, 0(1)
Authors:Wang Runtian  Jiang Shaohao  Zhang Hongzhong  Yao ShukunZhou Xuemin  Liu Wenhu  Zhu Tienian  Wang Huifen
Affiliation:Institute of Basic Medicine
Abstract:
With LAK cells from fetal splenocytes plus rIL-2,51 cases of malignant patients at the coddle and advanced stages were treated. Of them,3 cases were complete response (CR),7 cases partial response (PR),and curative effects were 19. 6%(CR+PR) or 31.4% (CR+PR+MR).In most of the patients,the clinical symptoms and living quality were improved,and the periods of survival extended. No severe toxic side effects werefound.
Keywords:LAK cells from fetal splenocytes  rLL-2  adoptive immunotherapy  cancer  
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