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甲状腺激素变化对急性创伤严重程度和预后的估价
引用本文:李景煜,林占堂,胡南方. 甲状腺激素变化对急性创伤严重程度和预后的估价[J]. 华中科技大学学报(医学版), 1989, 0(Z2)
作者姓名:李景煜  林占堂  胡南方
作者单位:同济医科大学附属同济医院急诊外科(李景煜,林占堂),同济医科大学附属同济医院急诊外科(胡南方)
摘    要:
作者用放免方法测定了52例急性创伤病人血清中四碘甲腺原氨酸(T_4),三碘甲腺原氨酸(T_3),游离T_4指数(FT_4I),反T_3(rT_3),T_3摄取比率(T_3RUR)的水平,并测定35例正常人作对照。结果表明:创伤病人血清中T_4,FT_4I,T_3水平明显降低;rT_3,T_3RUR显著升高,同正常人比较,有极显著意义(P<0.001)。随创伤严重程度不同,血清中T_4,FT_4I,T_3RUR水平也随之变化。当rT_3值升高到一定程度(0.69nmol/L)时,死亡率极高。

关 键 词:创伤  甲状腺激素

The Significance of Changes in Serum Thyroid Hormone in the Assessment of Severity and Prognosis of Acute Trauma
Li Jingyu,Lin Zhantang,Hu LanfangEmergency Surgery Department,Tongji Hospital,Tongji Medical University,Wuhan. The Significance of Changes in Serum Thyroid Hormone in the Assessment of Severity and Prognosis of Acute Trauma[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1989, 0(Z2)
Authors:Li Jingyu  Lin Zhantang  Hu LanfangEmergency Surgery Department  Tongji Hospital  Tongji Medical University  Wuhan
Abstract:
Levels of Tetraiothyronine (T4), Triiodonthyronine (T3), free T4 index (FT4I),reverse T3(rT3)andT3 resin uptuke ratio(T3RUR)in serum of 52 acute trauma patients were measured with radioimmunoassay (RIA), and 35 normal persons served as controls.The results showed that the levels of T4, FT4I, T3 in serum of trauma patients decreased obviously and levels of rT3, T3RUR increased markedly. The changes were very significant as compared with the normal in controls (P<0.001). Levels of T4, FT4I, T3RUR in serum varied with the severity of trauma. A very high mortality rate was found in patients with rT3 lever over 0.69nmol/L.
Keywords:trauma  thyroid hormone
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