中西医结合治疗肥胖型2型糖尿病60例疗效观察

目的观察中西医结合治疗肥胖型2型糖尿病的临床疗效,并探讨其作用机制。方法将120例肥胖型2型糖尿病患者随机分为2组。对照组60例口服降糖药二甲双胍2片,每日3次。治疗组60例在对照组治疗基础上加服养阴清热活血消脂汤,每日1剂,每日服3次。2组均6周为1个疗程,1个疗程后统计疗效。结果治疗组总有效率78.3%,对照组总有效率58.3%,2组比较差异有统计学意义(P<0.05)。治疗组在降低总胆固醇、甘油三酯,改善全血黏度(高切、低切)、血浆黏度、红细胞比积、纤维蛋白原方面明显优于对照组(P<0.05,P<0.01)。结论中西医结合治疗肥胖型2型糖尿病能有效减轻患者的症状,改善微循环及脂肪代谢,临床疗效确切。

Study of effect of integrated traditional Chinese medicine and western medicine on obese patients with type 2 diabetes mellitus

Objective To observe the clinic effect of integrated Traditional Chinese Medicine and western medicine on obese patients with type 2 diabetes mellitus and to find its mechanisms. Methods 120 obese patients with type 2 diabetes mellitus were randomly divided into control group and treatment group. The patients in the control group were given metformin hydrochloride 2 tablets, tid. The patients in the treatment group were given Yangyinqingre-huoxueqingzhi decoction 1dose, tid. in addition to the same treatment as the ones in the control group. The course of both groups were 6 weeks. Results The total effective rate was more significant in treatment group (78.3%) than that in control group (58.3%, P<0.05). Total cholesterol (TC), triglyceride (TG),high and low shear, plasma viscosity, hematocrit and fibrinogen in treatment group were reduced more obviously compared with those in control group (P<0.05,P<0.01). Conclusion Integrated Western medicine and Traditional Chinese Medicine in treating diabetes can not only alleviate the symptoms of the patients but also improve the fat metabolism and microcirculation. It has better effects on diabetes than only use western medicine.