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Familiality of major depressive disorder and patterns of lifetime comorbidity. The NEMESIS and GenMood studies |
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| Authors: | Maaike Verhagen Annemarie van der Meij Barbara Franke Wilma A. M. Vollebergh Ron de Graaf Jan K. Buitelaar Joost G. E. Janzing |
| Affiliation: | (1) Department of Psychiatry (966), Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB Nijmegen, The Netherlands;(2) Department of Human Genetics (855) and Department of Psychiatry (966), Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB Nijmegen, The Netherlands;(3) Netherlands Institute of Mental Health and Addiction, Da Costakade 45, 3521 VS Utrecht, The Netherlands;(4) Faculty of Social and Behavioral Sciences, University of Utrecht, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands; |
| Abstract: | BackgroundMajor depressive disorder (MDD) aggregates in families and is associated with high rates of lifetime axis-I comorbidity. This study examined whether familiality of MDD is associated with the presence of specific comorbid disorders, which might be an important factor to be taken into account in MDD treatment and research into MDD etiology. |
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