| 孕鼠被动吸烟对子代学习记忆功能及海马神经生长因子含量的影响 |
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| 引用本文： | 李芳兰,马太芳.孕鼠被动吸烟对子代学习记忆功能及海马神经生长因子含量的影响[J].解剖学报,2003,34(2):205-207. |
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| 作者姓名： | 李芳兰 马太芳 |
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| 作者单位： | 山西医科大学汾阳学院,汾阳,032200 |
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| 基金项目： | 山西省 2 0 0 0科技开发项目 ( 2 0 3 2 ) |
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| 摘 要： | 目的 探讨孕鼠被动吸烟对子代学习记忆功能的影响及其机制。方法 采用反映学习记忆功能的水迷宫法测试大鼠神经行为的改变，IRMA法测定大鼠海马神经生长因子的含量变化。结果 孕期被动吸烟使仔鼠学习记忆能力下降，海马神经生长因子含量明显降低。结论 孕期被动吸烟降低仔鼠学习记忆功能与海马神经生长因子代谢的失调有关。
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| 关 键 词： | 被动吸烟 子代 学习记忆功能 海马神经生长因子 含量 神经行为 |
FFECT OF THE CIGARETTE SMOKING ON LEARNING, MEMORY AND NERVE GROWTH FACTOR OF HIPPOCAMPUS IN DESCENDANTS OF PASSIVE SMOKING PREGNANT RAT |
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| LI Fang lan,MA Tai fang.FFECT OF THE CIGARETTE SMOKING ON LEARNING, MEMORY AND NERVE GROWTH FACTOR OF HIPPOCAMPUS IN DESCENDANTS OF PASSIVE SMOKING PREGNANT RAT[J].Acta Anatomica Sinica,2003,34(2):205-207. |
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| Authors: | LI Fang lan MA Tai fang |
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| Institution: | LI Fang lan * MA Tai fang |
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| Abstract: | Objective To study the effects of cigarette smoking on learning and memory ability in rat descendants and its mechanism. Methods Spatial water maze test was applied.Nerve growth factor contents in hippocampus was determimed by IRMA. Results The learning and memory abilities were declined and the nerve growth factor contents in the hippocampus were significantly depressed.Conclusion The effects of cigarette smoking on learning and memory function are highly correlated with the changes in nerve growth factor contents in the hippocampus. |
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| Keywords: | Cigarette smoking Neurobehavior Learning and memory Nerve growth factor Pregnant rat |
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