Aziridines and aziridinium ions in the practical synthesis of pharmaceutical intermediates--a perspective |
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Authors: | Dahanukar Vilas H Zavialov Ilia A |
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Affiliation: | Schering-Plough Research Institute, Department of Synthetic Chemistry, 1011 Morris Avenue, Mailstop U-3-2-2100, Union, NJ 07083, USA. vilas.dahanukar@spcorp.com |
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Abstract: | Recent methods for the synthesis of aziridines and aziridinium ions, the mechanisms of their nucleophilic ring-opening reactions and applications to the practical synthesis of pharmaceutical intermediates are reviewed. |
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