应用组织多普勒Tei指数评价高血压患者左心室功能的研究

目的:探讨Tei指数评价原发性高血压左室功能的临床价值。方法:选择原发性高血压患者61例,根据左心室重量指数分为两组,无心肌肥厚组(A组)31例,心肌肥厚组(B组)30例,另选30例健康体检者为对照组。以常规超声测量左室内径(LVEDD),舒张期二尖瓣口正向血流峰值比(E/A)与左室射血分数(EF)应用TDI技术于心尖四腔观获取二尖瓣环心肌运动频谱图,分别测量Sm、Em及Am;计算出Em/Am、Tei指数。结果:LVEDD、LVEF及Sm在3组间差异无显著性。Em、Am及Em/Am在A、B两组患者显著降低,尤其以B组明显,A、B组E/A均<1(P<0.05);高血压各组Tei指数比对照组呈递增性增高(P<0.001)。结论:Tei指数能简便、敏感、综合评价高血压左室功能。

Tissue doppler Tei index evaluation on left ventricular function in patients with hypertension

Objective: To investigate the clinical value of tissue Doppler Tei index in the evaluation of right ventricular function in patients with hypertension.Methods:Sixty-one patients with mild/moderate hypertension were divided into 2 groups.Thirty-one patients with normal left ventricular mass index(LVMI) were studied in group A,Thirty patients with increased LVMI in group B,and 30 healthy subjects served as control group.The conventional echo-Doppler parameters assessed included the LVEDD,E/A ratio and ejection fraction(EF).The mitral annulus motion was obtained by tissue Doppler imaging(TDI).The peak systolic and early and late diastolic velocities were measured respectively.The Tei index by TDI were calculated.Results:Compared to control group,the Tei index of RV in hypertension group was significantly increased(P<0.05).The Em,Am and Em/Am of the study groups were significantly lower than that of control group,E/A ratio in groups A and B was all less than 1(P<0.05)The Tei index in groups A and B was all greater than the control group and progressively increased(P<0.001).Conclusion The Tei index would be valuable and simple for estimating the left ventricular systolic and diastolic functions with high sensitivity in hypertension patients.