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The central nervous system in childhood chronic kidney disease
Authors:Debbie S. Gipson  Peter J. Duquette  Phil F. Icard  Stephen R. Hooper
Affiliation:(1) UNC Kidney Center, University of North Carolina School of Medicine, 7012 Burnett Womack Bldg., CB# 7155, Chapel Hill, NC 27599-7155, USA;(2) School of Education, University of North Carolina, Chapel Hill, NC, USA;(3) Clinical Center for Development and Learning, University of North Carolina School of Medicine, Chapel Hill, NC, USA;(4) Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC, USA
Abstract:
Neurodevelopmental deficits in pediatric and adult survivors of childhood onset chronic kidney disease (CKD) have been documented for many years. This paper reviews the available literature on central nervous system involvement incurred in childhood CKD. The studies reviewed include recent work in neuroimaging, electrophysiology, and neuropsychology, along with commentary on school functioning and long-term outcomes. The paper concludes with suggestions for monitoring the neurodevelopmental status and pursuing appropriate early interventions for children with CKD.
Keywords:Kidney failure  Central nervous system  Learning  Education  Children
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