Patient with liver cirrhosis presenting with necrotizing fasciitis due to Acinetobacter junii: A case report and literature review期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Patient with liver cirrhosis presenting with necrotizing fasciitis due to Acinetobacter junii: A case report and literature review

Affiliation:	1. Department of Infectious Disease, Kameda Medical Center, 929 Higashi-cho, Kamogawa Chiba, 296-8602, Japan;2. Department of General Internal Medicine, Kameda Medical Center, 929 Higashi-cho, Kamogawa Chiba, 296-8602, Japan;1. Department of Internal Medicine & Infectious Diseases, University Hospital of Heraklion, School of Medicine, University of Crete, 71110 Voutes, Heraklion, Crete, Greece;2. Department of Clinical Microbiology, University Hospital of Heraklion, School of Medicine, University of Crete, 71110 Voutes, Heraklion, Crete, Greece;3. National Reference Laboratory for Staphylococci, Department of Microbiology, School of Medicine, University of Patras, Patras, Greece;1. Departamento de Enfermedades Infecciosas, Hospital de Infectología, Centro Médico Nacional “La Raza”, Instituto Mexicano del Seguro Social, IMSS, Mexico City, Mexico;2. Departamento de Microbiología, Biomedicina y Biotecnología Molecular, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, IPN, Mexico City, Mexico;3. Centro de Simulación Médica, Facultad Mexicana de Medicina, Universidad La Salle, Mexico City, Mexico;4. Laboratorio Central de Epidemiología, División de Laboratorios de Vigilancia e Investigación Epidemiológica, CMN “La Raza”, Instituto Mexicano del Seguro Social, IMSS, Mexico City, Mexico;5. Unidad de Investigación en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, IMSS, Mexico City, Mexico;6. Departamento de Patología Clínica, Banco Central de Sangre, CMN “La Raza”, Instituto Mexicano del Seguro Social, IMSS, Mexico City, Mexico;7. Laboratorio de Urgencias, Hospital de Infectología, Instituto Mexicano del Seguro Social, IMSS, Mexico City, Mexico;8. Center for HIV and Hepatogastroenterology, Duesseldorf, Germany;1. Eiju General Hospital, Taito-ku, Tokyo 110-8645, Japan;2. Kawasaki City Institute for Public Health, Kawasaki, Kanagawa 210-0834, Japan;3. Zama Children''s Clinic, Zama, Kanagawa 252-0023, Japan;4. Ichikawa Children''s Clinic, Isehara, Kanagawa 259-1133, Japan;5. Abe Children''s Clinic, Yokohama, Kanagawa, 223-0051, Japan;6. Yasumi Hospital, Morioka, Iwate 028-4125, Japan;7. Ichikawa Clinic, Fukushima-shi, Fukushima 960-0112, Japan;8. Futaba Children''s Clinic, Ushiku, Ibaraki 300-1207, Japan;9. Junseikai Yoshihara Clinic, Takasaki, Gunma 370-3524, Japan;10. Shiozaki Clinic, Wakayama, Wakayama 640-8482, Japan;11. Wakaayukai Baba Clinic, Nagaokakyou, Kyoto 617-0814, Japan;12. Kudo Clinic, Kakogawa, Hyogo 675-0018, Japan;13. Maebashi Kita Hospital, Maebashi, Gunma 371-0054, Japan;14. Jinjikai Takahashi Clinic, Bando, Ibaraki 306-0631, Japan;15. Yokohama City Institute of Public Health, Yokohama, Kanagawa 236-0051, Japan;1. Infection Control Division, South Miyagi Medical Center, Aza-Nishi 38-1, Ogawara, Shibata-gun, Miyagi 989-1253, Japan;2. Department of Emergency and Critical Care Medicine, South Miyagi Medical Center, Aza-Nishi 38-1, Ogawara, Shibata-gun, Miyagi 989-1253, Japan;1. Department of Pulmonology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan;2. Respiratory Disease Center, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Japan;3. Department of Respiratory Medicine, Yokohama Minamikyousai Hospital, 1-21-1 Mutsuurahigashi, Kanazawa-ku, Yokohama, 236-0037, Japan;1. Department of Pharmacy, National Hospital Organization Beppu Medical Center, 1473 Uchikamado, Beppu, Oita, 874-0011, Japan;2. Center for Pharmacist Education, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba, 274-8555, Japan;3. Department of Pharmacy, National Hospital Organization Kyushu Medical Center, 1–8–1 Jigyohama, Chuo-ku, Fukuoka, 810-8563, Japan;4. Department of Medical Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama City, Toyama, 930-0194, Japan;5. Department of Clinical Infectious Diseases, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, 2630 Sugitani, Toyama City, Toyama, 930-0194, Japan

Abstract:	Acinetobacter spp. are known to be a cause of nosocomial infections and to have diverse mechanisms of resistance to antimicrobials. Here, we report the case of a patient who presented to our emergency department with necrotizing fasciitis due to Acinetobacter junii as confirmed by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry (MALDI-TOF MS). Patients with liver cirrhosis are susceptible to gram-negative infection. Moreover, although Acinetobacter spp. infection is best known to be a cause of combat-related-skin and soft-tissue infections, we propose that medical professionals need to consider the presence of these potentially multi-drug-resistant, gram-negative pathogens when treating patients with liver cirrhosis who present with severe soft-tissue infections. To our knowledge, this is the first case report of severe-skin and soft-tissue infections caused by A. junii.

Keywords:	Necrotizing fasciitis Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry" },{" #name" :" keyword" ," $" :{" id" :" kwrd0030" }," $$" :[{" #name" :" text" ," _" :" (MALDI-TOF MS) Emergency Department" },{" #name" :" keyword" ," $" :{" id" :" kwrd0040" }," $$" :[{" #name" :" text" ," _" :" (ED)
本文献已被 ScienceDirect 等数据库收录！

设为首页 | 免责声明 | 关于勤云 | 加入收藏