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液体活组织检查在泌尿系肿瘤中的研究进展
引用本文:熊波波,张劲松,李宁,王海峰,左毅刚,王剑松. 液体活组织检查在泌尿系肿瘤中的研究进展[J]. 肿瘤研究与临床, 2020, 0(2): 140-144
作者姓名:熊波波  张劲松  李宁  王海峰  左毅刚  王剑松
作者单位:昆明医科大学第二附属医院泌尿外科
基金项目:国家自然科学基金(81660422、81660423)。
摘    要:泌尿系恶性肿瘤是一种发病率和病死率较高的疾病,早期发现、诊断、治疗反应和预后预测可以显著改善患者的生命质量。无创液体活组织检查的发展代表了精准医学领域的重大创新,开辟了癌症的精准医学和个体化治疗计划的新时代。循环生物标志物在泌尿系肿瘤的诊断、治疗反应和预后中显示出巨大的潜在效用。文章就液体活组织检查在泌尿系肿瘤中的研究进展进行综述。

关 键 词:泌尿系肿瘤  前列腺肿瘤  肿瘤细胞,循环  液体活组织检查  外泌体

Progress of liquid biopsy in urinary neoplams
Xiong Bobo,Zhang Jinsong,Li Ning,Wang Haifeng,Zuo Yigang,Wang Jiansong. Progress of liquid biopsy in urinary neoplams[J]. Cancer Research and Clinic, 2020, 0(2): 140-144
Authors:Xiong Bobo  Zhang Jinsong  Li Ning  Wang Haifeng  Zuo Yigang  Wang Jiansong
Affiliation:(Department of Urology,the Second Affiliated Hospital of Kunming Medical University,Yunnan Institute of Urology,Kunming 650101,China)
Abstract:Urinary malignancy is a disease with high morbidity and mortality.Early detection,diagnosis,treatment response and prognosis can significantly improve patients'quality of life.The development of non-invasive liquid biopsy represents a major innovation in the field of precision medicine,opening up a new era for precision medicine and individualized treatment of cancer.Circulating biomarkers have shown a great potential utility in the diagnosis,treatment response,and prognosis of urinary tumors.This paper reviews the recent progress of liquid biopsy in urinary neoplasms.
Keywords:Urologic neoplasms  Prostate neoplasms  Tumor cells,circulation  Liquid biopsy  Exosomes
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