双肺移植治疗儿童囊性纤维化的多学科综合诊疗

目的  通过多学科综合诊疗（MDT）模式提高双肺移植治疗儿童囊性纤维化的外科疗效。方法  对1例国内罕见的终末期囊性纤维化10岁患儿进行肺移植术前MDT讨论，制定对应治疗方案。结果  患儿确诊囊性纤维化5年，肺移植指征明确，经过MDT讨论决定行Clam-shell切口下双肺移植术，术中维持生命体征稳定，术后给予呼吸机辅助通气、抗感染、免疫抑制、抑酸和预防应激性溃疡等治疗，并根据患儿特点给予个体化治疗方案，术后恢复良好。结论  通过肺移植术前MDT讨论，肺移植治疗儿童囊性纤维化的手术效果满意，减少了术后并发症的发生风险，值得临床推广。

Multi-disciplinary team of the treatment of bilateral lung transplantation for pediatric cystic fibrosis

Objective To improve the surgical efficacy of bilateral lung transplantation for pediatric cystic fibrosis through multi-disciplinary team (MDT). Methods Preoperative MDT consultation was delivered for a 10-year-old child with rare end-stage cystic fibrosis to establish the corresponding treatment protocol. Results The child was diagnosed with cystic fibrosis for 5 years, and the indication of lung transplantation were confirmed. After preoperative MDT consultation, bilateral lung transplantation via a Clam-shell incision was determined. The vital signs were maintained stable during operation. Postoperatively, ventilator-assisted ventilation, anti-infection, immunosuppression, acid suppression, prevention of stress ulceration and other treatments were delivered. Individualized treatment was given according to the characteristics of the child, and the child was well recovered. Conclusions Through preoperative MDT consultation, lung transplantation yields satisfactory surgical efficacy in treating pediatric cystic fibrosis and lowers the risk of postoperative complications, which deserves application in clinical practice.