刺五加联合尼莫地平对原发性闭角型青光眼的临床疗效观察

目的:观察口服刺五加联合尼莫地平片对原发性闭角型青光眼视神经损害的临床疗效。方法:原发性闭角型青光眼术后眼压控制正常的患者25例(35跟),随机分为观察组14例(21眼),口服刺五加联合尼莫地平治疗,对照组11例(14眼),仅口服肌苷片,治疗后3月两组进行闪光视网膜电图(F-ERG)及图形视诱发电位(P-VEP)的检查。结果:观察组F-ERG的b波振幅值、P-VEP的P100波潜伏时及振幅值改善明显高于对照组(P<0.05)。观察组F-ERG的b波潜伏时较对照组有所提前。结论:刺五加药片联合尼莫地平可改善原发性闭角型青光眼视功能损害。

The effect of acanthopanax senticosus and nimodipine on the electrophysiology test of primary angle-closed glaucoma

Objective: To study the effect of acanthopanax senticosus and nimodipine tablets on primary angle-closed glau-coma(PACG). Methods: The patients with primary angle-closed glaucoma who had normal intraocular pressure after operation were divided into two groups randomly, 14 patients(21 eyes) treated with acanthopanax senticosus and nimodipine tablets for 3 months and 11 patients(14 eyes) with inosine tablets as control group. All patients were examined by flash electroretinography (F-ERG) and pattern visual evoked potential (P-VEP).Results: Compared with control group, there was a significant improvements in the amplitude of b wave in F-ERG, and in the amplitude and latent time of P100 wave in treated group(P<0.05), and also there was an improvements in the latent time of b wave .Conclusion: The use of acanthopanax senticosus and nimodipine tablets can improve the visual function in patients with PACG.