Assignment of the gene determining human carbonic anhydrase, CAI, to chromosome 8 |
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| Authors: | Y. H. EDWARDS,J. H. BARLOW&dagger ,C.P. KONIALIS&dagger ,S. POVEY,P.H.W. BUTTERWORTH&dagger |
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| Affiliation: | *M.R.C. Human Biochemical Genetics Unit, The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE;†Biochemistry Department, University College London, Gower Street, London, WC1E 6BT |
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| Abstract: | A cDNA clone complementary to the mRNA encoding the rabbit erythrocyte specific carbonic anhydrase, CAI, has been used as probe for human CAI sequences in the analysis of DNA from panels of rodent/human somatic cell hybrids. The presence of the human CAI gene in all hybrids correlates with the presence of chromosome 8. Together with published mapping data, this assignment indicates that three CA loci are situated on chromosome 8. |
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