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Nationwide Surveillance of Macrolide-Resistant Mycoplasma pneumoniae Infection in Pediatric Patients |
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| Authors: | Yasuhiro Kawai Naoyuki Miyashita Mika Kubo Hiroto Akaike Atsushi Kato Yoko Nishizawa Aki Saito Eisuke Kondo Hideto Teranishi Tokio Wakabayashi Satoko Ogita Takaaki Tanaka Kozo Kawasaki Takashi Nakano Kihei Terada Kazunobu Ouchi |
| Affiliation: | Department of Pediatricsa;Department of Internal Medicine 1,b Kawasaki Medical School, Okayama, Japan |
| Abstract: | We conducted nationwide surveillance to investigate regional differences in macrolide-resistant (MR) Mycoplasma pneumoniae strains in Japan. The prevalence of MR M. pneumoniae in pediatric patients gradually increased between 2008 and 2012. Although regional differences were observed, high levels of MR genes were detected in all seven surveillance areas throughout Japan and ranged in prevalence from 50% to 93%. These regional differences were closely related to the previous administration of macrolides. |
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