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接触温石棉女工恶性肿瘤死亡的队列研究
引用本文:张幸,孙统达,施南峰,朱丽秋,森永谦二. 接触温石棉女工恶性肿瘤死亡的队列研究[J]. 国际流行病学传染病学杂志, 2006, 33(1): 12-14
作者姓名:张幸  孙统达  施南峰  朱丽秋  森永谦二
作者单位:浙江省医学科学院卫生学研究所;慈溪市疾病预防控制中心;日本国立工业卫生研究所
摘    要:目的调查接触温石棉女工的恶性肿瘤死亡率。方法以1960年1月1日至1980年12月31日曾经从事家庭内温石棉手工纺织作业一年以上的女工为调查对象,采用历史性队列流行病学方法进行研究。结果在5681名接触温石棉纺织女工中,有144名死于癌症,其中有74名女工死于肺癌,病死率最高;其次为肝癌,死亡数为27例;占第三位的是胃癌,死亡数为18例。以当地女性年龄组别恶性肿瘤死亡率均值为对照组计算标准化死亡比(SMR),所有除肺癌外的恶性肿瘤与肺癌的SMR分别为1.16(P<0.05)和4.17(P<0.01)。结论接触温石棉的女性纺织工人有明显的肺癌死亡高发倾向。

关 键 词:肿瘤  石棉  死亡率
收稿时间:2006-01-10
修稿时间:2006-01-10

Survey on the mortality of malignant tumors in female workers exposed to chrysotile asbestos
Zhang Xing,Sun Tong-da,Shi Nan-feng,Zhu Li-qiu,Kenji Morinaga. Survey on the mortality of malignant tumors in female workers exposed to chrysotile asbestos[J]. International Journal of Epidemiology and Infectious Disease, 2006, 33(1): 12-14
Authors:Zhang Xing  Sun Tong-da  Shi Nan-feng  Zhu Li-qiu  Kenji Morinaga
Affiliation:1,Institute of Hygiene, Zhejiang Academy of Medical Sciences, nangzhou 310013, China;2,Cixi Municipal Center for Disease Control and Prevention, Cixl 315300, China;3,National institute of Irolustial Health, Kawasaki,japan
Abstract:Objective To investigate the mortality of malignant tumor in female workers exposed to chrysotile asbestos. Methods A retrospective cohort study of female workers was conducted, who had been engaged in the manual spinning of chrysotile in family with more than one year between January 1, 1960 and December 31, 1980. Results A total of 144 persons were found to be dead from cancer. Among them the most frequent was lung cancer (74), and the second liver cancer (27), and the third stomach cancer (18). Standardized mortality ratio (SMR) from total malignant tumor and lung cancer were 1.16 (P<0.05) and 4.17 (P<0.01) respectively, based on the control population of the same region. Conclusion A significant excess death from lung cancer was found among female workers who had been exposed to chrysotile.
Keywords:Tumor  Chrysotile  Mortality
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