| 舍曲林与氯丙咪嗪治疗强迫症的对照研究 |
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| 引用本文： | 崔义才,董俊玲.舍曲林与氯丙咪嗪治疗强迫症的对照研究[J].山东精神医学,2004,17(1):21-22. |
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| 作者姓名： | 崔义才 董俊玲 |
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| 作者单位： | 山东省临沂市精神卫生中心,276005 |
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| 摘 要： | 目的比较舍曲林与氯丙咪嗪治疗强迫症的疗效和不良反应。方法应用舍曲林和氯丙咪嗪治疗强迫症各30例，应用Yale-Brown强迫量表、汉密顿抑郁量表(HAMD)、汉密顿焦虑量表(HAMA)及临床4级标准评定疗效。结果舍曲林与氯丙咪嗪治疗后Yale-Brown强迫量表分值、HAMD、HAMA分值均显著下降，两组间减分比较，差异无显著性，舍曲林不良反应发生率明显少于氯丙咪嗪。结论舍曲林治疗强迫症疗效与氯丙咪嗪相当，不良反应较轻，值得推广。
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| 关 键 词： | 舍曲林 氯丙咪嗪 强迫症 临床对照研究 不良反应 抗抑郁剂 |
| 文章编号： | 1009-7201(2004)-01-0021-02 |
| 修稿时间： | 2003年6月17日 |
A comparative study of sertraline and clomipramine in the treatment of obsessive-compulsive disorders |
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| Cui Yicai,Dong Junling.Linyi Municipal Mental Health Center,Shandong ,China.A comparative study of sertraline and clomipramine in the treatment of obsessive-compulsive disorders[J].Shangdong Archives of Psychiatry,2004,17(1):21-22. |
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| Authors: | Cui Yicai Dong JunlingLinyi Municipal Mental Health Center Shandong China |
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| Institution: | Cui Yicai,Dong Junling.Linyi Municipal Mental Health Center,Shandong 276005,China |
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| Abstract: | Objective To compare the efficacy and side effects of sertraline and clomipramine in the treatment of obsessive-compulsive disorders.Methods Sixty patients with obsessive-compulsive disorders were randomly assigned into sertraline group and clomipramine group.Efficacy and side effects were assessed with clinical evaluation,Yale-Brown Obsessive-compulsive Rating Scale,HAMD and HAMA.Results There was no significant difference in the efficacy between sertraline and clomipramine.The side effects of sertraline were lower than those of clomipramine.Conclusion Sertraline is an effective and safe drug in the treatment of obsessive-compulsive disorders. |
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| Keywords: | Sertraline Clomipramine Obsessive-compulsive disorder |
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