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系统性红斑狼疮并血栓病28例临床分析
引用本文:杨辉,尹松梅,谢双锋. 系统性红斑狼疮并血栓病28例临床分析[J]. 岭南急诊医学杂志, 2011, 16(1): 30-32. DOI: 10.3969/j.issn.1671-301X.2011.01.014
作者姓名:杨辉  尹松梅  谢双锋
作者单位:1. 广东顺德第一人民医院血液科,538300
2. 中山大学孙逸仙纪念医院血液科
摘    要:
目的:探讨系统性红斑狼疮(SLE)血栓形成的危险因素.方法:回顾性分析SLE并血栓病28例的临床资料.结果:28例中男6例,女22例,男女之比为1∶3.7;平均年龄(42.7±13.5)岁;平均病程(7.5±8.6)年;单因素分析显示:SLE-DAI、aCL、LDL-C、年龄、病程、男性、吸烟为血栓病的危险因素(P<0.05);多因素分析显示:病程、aCL、SLE-DAI是血栓病独立的危险因素(P<0.05).结论:SLE患者的病程长、aCL阳性、SLE-DAI≥10分是合并血栓性疾病的独立危险因素.

关 键 词:系统性红斑狼疮  血栓病  临床分析

Clinical Analysis of 28 Patients with Systemic Lupus Erythematosus Complicating Thrombus
YANG Hui,YIN Song-mei,XIE Shuang-feng. Clinical Analysis of 28 Patients with Systemic Lupus Erythematosus Complicating Thrombus[J]. Lingnan Journal of Emergency Medicine, 2011, 16(1): 30-32. DOI: 10.3969/j.issn.1671-301X.2011.01.014
Authors:YANG Hui  YIN Song-mei  XIE Shuang-feng
Affiliation:( Department of Hematology, the 1st People's Hospital of Shunde, Guangdong Province, 538300 2. Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou)
Abstract:
Objective: To explore the risk factors of patients with systemic lupus erythematosus (SLE) complicating thrombosis. Methods: The clinical data of 28 patients with SLE complicating thrombus were analyzed retrospectively. Results: Among the 28 cases, male were 6 cases and female were 22 cases, male vs female ratio was 1:3.7. The average age was 42.7±13.5 years. The average life duration was 7.5±8.6 years. Single factor analysis showed that SLE-DAI, aCL, I,DL-C, age, duration, male, cigarette-smoking were risk factors for thrombus, all P〈 0.05. Multivariate analysis showed that duration, aCL,SLE-DAI were independent risk factors,all P〈0.05. Conslusion: Long-duration, aCL(+), SLE-DAI≥ 10 were independent risk factors for SLE complicating thrombus.
Keywords:systemic lupus erythematosus  thrombosis  clinical analysis
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